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Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer

Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller et al. • Pathology and Oncology Research (2025)

ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circ...

DOAJ Open Access (DOAJ) DOI: 10.3389/pore.2024.1611929

El higienista Manuel Pizarro Jiménez (1821-1892) y su discurso doctrinal «De la prostitución y de su influencia en las costumbres, en la moralidad y en la salud pública» (1870)

Juan L. Carrillo, Encarnación Bernal, María Luisa Calero • Asclepio: Revista de Historia de la Medicina y de la Ciencia (2007)

El presente artículo es una aproximación al problema de la prostitución en la España de la segunda mitad del siglo XIX. Se aporta el texto del «discurso doctrinal» que sirvió al higienista sevillano Manuel Pizarro Jiménez (1821-1892) para o...

DOAJ Open Access (DOAJ) DOI: 10.3989/asclepio.2007.v59.i1.221

Preoperative Radiological Findings Prior Endoscopic Dacryocystorhinostomy in Patients with Nasolacrimal Duct Obstruction

Heba Mahmoud Hamdy, Ahmed Abdelrahman • Zagazig University Medical Journal (2025)

Background: Epiphora is a common condition brought on by blockage of the nasolacrimal duct. In order to diagnose and treat these patients, it is critical to evaluate their lacrimal drainage system. This study aimed to identify and analyze t...

DOAJ Open Access (DOAJ) DOI: 10.21608/zumj.2025.395057.4007

Мигранты и Российское государство в XX веке: возможности и ограничения

Oleg Gorbachev • Quaestio Rossica (2018)

Статья продолжает тему «самовольных мигрантов», поднятую Л. Сигельбаумом и Л. П. Мох в работе “Escaping in Twentieth-Century Russia”. По мнению автора, Российское государство в течение большей части XX столетия наиболее остро реагировало на...

DOAJ Open Access (DOAJ) DOI: 10.15826/qr.2018.1.293

The Cardiorespiratory Network in Healthy First-Degree Relatives of Schizophrenic Patients

Steffen Schulz, Jens Haueisen, Karl-Jürgen Bär, Andreas Voss • Frontiers in Neuroscience (2020)

Impaired heart rate- and respiratory regulatory processes as a sign of an autonomic dysfunction seems to be obviously present in patients suffering from schizophrenia. Since the linear and non-linear couplings within the cardiorespiratory s...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2020.00617

Non-traumatic Causes of Brown-sequard Syndrome: A Case Series and Clinical Update With Systematic Review

Vaner Köksal, Mahmoud Osama, Mohammed Ali Alvi • Iranian Journal of Neurosurgery (2021)

Background and Importance: Brown-Sequard Syndrome (BSS) is a rare neurological condition resulting from a hemisection injury to or unilateral compression on the spinal cord. The common causes of BSS that are amenable to be treated surgicall...

DOAJ Open Access (DOAJ)

Why do emergency department clinicians miss acute aortic syndrome? A case series and descriptive analysis

Rachel McLatchie, Sarah Wilson, Matthew Reed, Francoise Ticehurst et al. • Emergency Care Journal (2023)

Objectives: To understand why the diagnosis of AAS is missed in the ED, and to characterise the presenting features of cases in which a diagnosis of AAS was missed. Methods: A retrospective case series cohort study was performed, identif...

DOAJ Open Access (DOAJ) DOI: 10.4081/ecj.2023.11153

Longevity of dental restorations in Sjogren’s disease patients using electronic dental and health record data

Grace Gomez Felix Gomez, Mei Wang, Zasim A. Siddiqui, Theresa Gonzalez et al. • BMC Oral Health (2024)

Abstract Background Decreased salivary secretion is not only a risk factor for carious lesions in Sjögren’s disease (SD) but also an indicator of deterioration of teeth with every restorative replacement. This study determined the longevity...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12903-024-03957-9

Facial Oedema Is Not Always Angioedema: A Case of Spontaneous Pneumomediastinum with Subcutaneous Emphysema during COPD Exacerbation

Sarah Damanti, Francesca Rosini, Daniela Mari, Maura Marcucci • European Journal of Case Reports in Internal Medicine (2015)

We report a case of acute facial oedema in an elderly hospitalized patient which was initially misdiagnosed as angioedema secondary to antibiotics in a patient with an allergic diathesis. We describe the differential aetiologies and then t...

DOAJ Open Access (DOAJ) DOI: 10.12890/2015_000281

Clinical Features of CINin ChineseVery Elderly Patients Undergoing Coronary Angiography Procedure With Hydration Treatment: A Three-Center, Prospective Study

Liwen Bao, Jun Bo, Bo Jin, Nanqing Xiong et al. • International Journal of Gerontology (2018)

Summary: Background: To assess the morbidity and risk factors of contrast induced nephropathy (CIN) in Chinese very elderly patients. Methods: The very elderly patients whose age ≥75 year-old, from North Huashan Hospital, South Renji Hospi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijge.2018.05.010

Procalcitonin-guided antibiotic therapy for pediatrics with infective disease: A updated meta-analyses and trial sequential analysis

Peng Li, JiaLe Liu, Junjun Liu • Frontiers in Cellular and Infection Microbiology (2022)

ObjectiveWe aimed to evaluate the effect of procalcitonin (PCT) guided therapy on antibiotic exposure in pediatric patients with infectious disease.MethodsWe performed an updated systematic review and meta-analysis of randomized controlled ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2022.915463

The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists

Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology (2024)

The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol31090369

The evaluation of changes in muscle strength in elderly patients with premature aging

Tatyana V. Pavlova, Kirill I. Proshchayev, Elmira E. Satarinova, Natalia B. Pilkevich et al. • Медицинский вестник Юга России (2019)

Purpose: to evaluate changes in muscle strength in elderly patients with signs of premature aging. Materials and methods: the study included 1080 people: 540 aged 44 to 54 years (mean age 49.1±2.2) and 540 at the age of 55 to 64 years (mean...

DOAJ Open Access (DOAJ) DOI: 10.21886/2219-8075-2019-10-1-59-64

Alpha-Band EEG Modulation as a Potential Aged-Related Biomarker for Biofeedback-Driven Motor–Cognitive Adaptability

Swapno Aditya, Adam Clarke, Lucy Armitage, Wing-Kai Lam et al. • Sensors (2026)

Background: Age-related changes in motor–cognitive function are associated with altered neural adaptability, particularly during tasks requiring integration of cognitive and motor processes. Dual-task paradigms are commonly used to assess s...

DOAJ Open Access (DOAJ) DOI: 10.3390/s26144575

Why did an effective Dutch complex psycho-social intervention for people with dementia not work in the German healthcare context? Lessons learnt from a process evaluation alongside a multicentre RCT

Sebastian Voigt-Radloff, Maud Graff, Myrra Vernooij-Dassen, Rainer Leonhart et al. • BMJ Open (2011)

Background The positive effects of the Dutch Community Occupational Therapy in Dementia programme on patients' daily functioning were not found in a multicentre randomised controlled trial (RCT) in Germany.Objectives To evaluate possible ef...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2011-000094

Changes in daily living dependency and incident depressive symptoms among older individuals: findings from four prospective cohort studies

Hongwei Liu, Juxiang Yang, Gang Song, Minheng Zhang et al. • BMJ Mental Health (2025)

Background With rapid population ageing, depressive symptoms in older adults have become a pressing public health concern. While functional dependency is a known risk factor, the impact of changes in dependency over time remains unclear.Obj...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjment-2025-301749

Risk Profiles for Falls among Older Adults: New Directions for Prevention

William A. Satariano, Constance Wang, Melissa E. Kealey, Elaine Kurtovich et al. • Frontiers in Public Health (2017)

ObjectiveTo address whether neighborhood factors, together with older adults’ levels of health and functioning, suggest new combinations of risk factors for falls and new directions for prevention. To explore the utility of Grade-of-Members...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2017.00142

Social Support, Social Participation, and Life Accomplishment of Older Adult Residents of Assisted Living Facilities and Their Adjoining Communities

Christopher Olusanjo Akosile PhD, Chisom Onyekwuluje BMR, Ukamaka Gloria Mgbeojedo PhD, Emmanuel Chiebuka Okoye PhD et al. • Gerontology and Geriatric Medicine (2023)

Objectives: To assess and compare levels of social support (SS), social participation (SP) and life accomplishment (LA) among older adults in some assisted-living facilities (ALFs) and their community-dwelling (CD) peers. Methods: One hundr...

DOAJ Open Access (DOAJ) DOI: 10.1177/23337214231218797

Epigenetic Age Acceleration and Hearing: Observations From the Baltimore Longitudinal Study of Aging

Pei-Lun Kuo, Ann Zenobia Moore, Frank R. Lin, Frank R. Lin et al. • Frontiers in Aging Neuroscience (2021)

Objectives: Age-related hearing loss (ARHL) is highly prevalent among older adults, but the potential mechanisms and predictive markers for ARHL are lacking. Epigenetic age acceleration has been shown to be predictive of many age-associated...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnagi.2021.790926

Aging, aerobic exercise, and cardiovascular health: Barriers, alternative strategies and future directions

Kevin O. Murray, Sophia A. Mahoney, Ravinandan Venkatasubramanian, Douglas R. Seals et al. • Experimental Gerontology (2023)

Age-associated cardiovascular (CV) dysfunction, namely arterial dysfunction, is a key antecedent to the development of CV disease (CVD). Arterial dysfunction with aging is characterized by impaired vascular endothelial function and stiffeni...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2023.112105