Academic Articles & Research Papers

Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVI...

Adherence and health care costs

Aurel O Iuga,1,2 Maura J McGuire3,4 1Johns Hopkins Bloomberg School of Public Health, 2Johns Hopkins University, 3Johns Hopkins Community Physicians, 4Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Medication non...

Public–private partnership in pipelining science of acute care ecosystem: Insights from Taiwan's Presidential Hackathon

Abstract Introduction The acute care system faced significant challenges in managing healthcare emergencies due to a lack of coordination between emergency services and logistical support. This disorganization undermined collaboration and r...

Why do healthcare professionals fail to escalate as per the early warning system (EWS) protocol? A qualitative evidence synthesis of the barriers and facilitators of escalation

Abstract Background Early warning systems (EWSs) are used to assist clinical judgment in the detection of acute deterioration to avoid or reduce adverse events including unanticipated cardiopulmonary arrest, admission to the intensive care ...

Healthcare Management

Healthcare Management takes a look at international perspectives in healthcare management and the way regional priorities, national income, and social factors are crucial to effective healthcare services. Readers are provided the skills to ...

Big Data in Healthcare Management: A Review of Literature

A systematic literature review of papers on big data in healthcare published between 2010 and 2015 was conducted. This paper reviews the definition, process, and use of big data in healthcare management. Unstructured data are growing very f...

A Blockchain-Based Smart Contract System for Healthcare Management

Blockchain is evolving to be a secure and reliable platform for secure data sharing in application areas such as the financial sector, supply chain management, food industry, energy sector, internet of things and healthcare. In this paper, ...

Alpha-Synuclein Induced Immune Cells Activation and Associated Therapy in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder closely related to immunity. An important aspect of the pathogenesis of PD is the interaction between α-synuclein and a series of immune cells. Studies have shown that accumulation of...

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific...

Editorial: Listening in action: Attention, emotions and cognition in the auditory system

Necroptosis and Neuroinflammation in Retinal Degeneration

Necroptosis mediates the chronic inflammatory phenotype in neurodegeneration. Receptor-interacting protein kinase (RIPK) plays a pivotal role in the induction of necroptosis in various cell types, including microglia, and it is implicated i...

Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by accumulation of fragmented insoluble TDP-43 and loss of TDP-43 from the nucleus. Increased expression of exogenous TARDBP (encoding TDP-43) induces TDP-43 p...

Neuroscience in Medicine

Cytology and Organization of Cell Types: Light and Electron Microscopy Rochelle S. Cohen and Donald W. Pfaff Anatomy of the Spinal Cord and Brain Bruce E. Maley Ion Channels and Electrical Signaling Stanko S. Stojilkovic A. Clinical Correla...

Computational Neuroscience

The ultimate aim of computational neuroscience is to explain how electrical and chemical signals are used in the brain to represent and process information. This goal is not new, but much has changed in the last decade. More is known now ab...

The Cognitive Neurosciences

The sixth edition of the foundational reference on cognitive neuroscience, with entirely new material that covers the latest research, experimental approaches, and measurement methodologies. Each edition of this classic reference has proved...

Dynamical Systems in Neuroscience

Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order...

Circular RNA expression profiles and functional predication after restraint stress in the amygdala of rats

Prolonged or repeated exposure to stress elevates the risk of various psychological diseases, many of which are characterized by central nervous system dysfunction. Recent studies have demonstrated that circular RNAs (circRNAs) are highly a...

Age-Related Homeostatic Plasticity at Rodent Neuromuscular Junctions

Motor ability decline remains a major threat to the quality of life of the elderly. Although the later stages of aging co-exist with degenerative pathologies, the long process of aging is more complicated than a simple and gradual degenerat...

The Neuroscience of Language

How is language organized in the human brain? The Neuroscience of Language, published in 2003, puts forth a systematic model of language to bridge the gap between linguistics and neuroscience. Neuronal models of word and serial order proces...

The Cognitive Neurosciences

The fifth edition of a work that defines the field of cognitive neuroscience, with entirely new material that reflects recent advances in the field. Each edition of this classic reference has proved to be a benchmark in the developing field...