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Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

Kristoffer Strålin, Erik Wahlström, Sten Walther, Anna M Bennet-Bark et al. • The Lancet Regional Health. Europe (2021)

Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVI...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.lanepe.2021.100054

Adherence and health care costs

Iuga AO, McGuire MJ • Risk Management and Healthcare Policy (2014)

Aurel O Iuga,1,2 Maura J McGuire3,4 1Johns Hopkins Bloomberg School of Public Health, 2Johns Hopkins University, 3Johns Hopkins Community Physicians, 4Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Medication non...

DOAJ Open Access (DOAJ)

Healthcare management

Konrad Obermann, Christian Thielscher • Medical economics (2021)

Management: history and terminology Healthcare management is often defined as leadership and direction in organizations that deliver health-related services – such as hospitals, pharmaceutical companies and health maintenance organizations ...

OPENALEX DOI: https://doi.org/10.1017/9781788211918.006

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

Marie E Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri et al. • Nature Communications (2019)

DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-019-11150-8

Prevalence of Constipation in Elderly and Its Association With Dementia and Mild Cognitive Impairment: A Cross-Sectional Study

Fei Wang, Fei Wang, Min Fei, Min Fei et al. • Frontiers in Neuroscience (2022)

BackgroundConstipation and dementia have similar epidemiological characteristics. Changes in intestinal flora and characteristics of the brain-gut axis play roles in the pathogeneses of the two diseases, suggesting that there may be a close...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2021.821654

Alterations in white matter fiber density associated with structural MRI and metabolic PET lesions following multimodal therapy in glioma patients

Michel Friedrich, Ezequiel Farrher, Svenja Caspers, Svenja Caspers et al. • Frontiers in Oncology (2022)

BackgroundIn glioma patients, multimodality therapy and recurrent tumor can lead to structural brain tissue damage characterized by pathologic findings in MR and PET imaging. However, little is known about the impact of different types of d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.998069

Hamartin: An Endogenous Neuroprotective Molecule Induced by Hypoxic Preconditioning

Sijie Li, Sijie Li, Changhong Ren, Changhong Ren et al. • Frontiers in Genetics (2020)

Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved. Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such mol...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2020.582368

Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation

Akihiro Sugai, Taisuke Kato, Akihide Koyama, Yuka Koike et al. • Neurobiology of Disease (2019)

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by accumulation of fragmented insoluble TDP-43 and loss of TDP-43 from the nucleus. Increased expression of exogenous TARDBP (encoding TDP-43) induces TDP-43 p...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nbd.2019.104534

Neuroscience in Medicine

P. Michael Conn • Humana Press eBooks (2003)

Cytology and Organization of Cell Types: Light and Electron Microscopy Rochelle S. Cohen and Donald W. Pfaff Anatomy of the Spinal Cord and Brain Bruce E. Maley Ion Channels and Electrical Signaling Stanko S. Stojilkovic A. Clinical Correla...

OPENALEX DOI: https://doi.org/10.1007/978-1-59259-371-2

The Cognitive Neurosciences

Laurel J. Buxbaum, Solène Kalénine • The MIT Press eBooks (2020)

The sixth edition of the foundational reference on cognitive neuroscience, with entirely new material that covers the latest research, experimental approaches, and measurement methodologies. Each edition of this classic reference has proved...

OPENALEX Open Access DOI: https://doi.org/10.7551/mitpress/11442.001.0001

Prefrontal cortical deficits are a putative susceptibility factor for PTSD

Rebecca Nalloor, Rebecca Nalloor, Khadijah Shanazz, Khadijah Shanazz et al. • Frontiers in Behavioral Neuroscience (2026)

IntroductionOnly a subset of people who experience a traumatic event develop Post-Traumatic Stress Disorder (PTSD) suggesting that there are susceptibility factors influencing PTSD pathophysiology. While post trauma sequelae factors are ext...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnbeh.2026.1750991

Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector

Jeanette Zanker, Daniela Hüser, Adrien Savy, Sara Lázaro-Petri et al. • Frontiers in Molecular Neuroscience (2023)

Viral vectors have become important tools for basic research and clinical gene therapy over the past years. However, in vitro testing of vector-derived transgene function can be challenging when specific post-translational modifications are...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2023.1280556

Toward an integrated approach for mental health and psychosocial support and peacebuilding in North-East Nigeria: programme description and preliminary outcomes from ‘Counselling on Wheels’

Sharli Paphitis, Fatima Akilu, Natasha Chilambo, Abiye Iruayenama et al. • BJPsych Open (2023)

Background Despite theoretical support for including mental health and psychosocial support (MHPSS) with peacebuilding, few programmes in conflict-affected regions fully integrate these approaches. Aims To describe and assess preliminary o...

DOAJ Open Access (DOAJ) DOI: 10.1192/bjo.2023.575

Encyclopedia of Neuroscience

Donna C. Bergen • JAMA (1988)

Notice the subject of this book: not "neurosciences" but "neuroscience." During the past 20 years, rapidly accelerating advances in neurochemistry, neurophysiology, neurobiology, neuropharmacology, neuroanatomy, etc, have brought about an e...

OPENALEX DOI: https://doi.org/10.1001/jama.1988.03410010112050

Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study

Pasquale Ambrosino, Ilenia Calcaterra, Antonio Molino, Pasquale Moretta et al. • Biomedicines (2021)

Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a case-control study to assess the alterations of endothelium-dependent flow-mediated...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines9080957

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Raife Dilek Turan, Cihan Tastan, Derya Dilek Kancagi, Bulut Yurtsever et al. • Scientific Reports (2021)

Abstract The SARS-CoV-2 virus caused the most severe pandemic around the world, and vaccine development for urgent use became a crucial issue. Inactivated virus formulated vaccines such as Hepatitis A and smallpox proved to be reliable appr...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-95086-4

Formation and stability of oil-in-water nanoemulsions containing rice bran oil: <it>in vitro </it>and <it>in vivo </it>assessments

Rocha-Filho Pedro A, Oliveira Gustavo C, Viera Gisely S, Bortoloto Josiane et al. • Journal of Nanobiotechnology (2011)

Abstract Background Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing prod...

DOAJ Open Access (DOAJ) DOI: 10.1186/1477-3155-9-44