Reset
Showing 20 of 6,095 academic articles

Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells

Yuki Ota, Takuya Kawanai, Ryo Watanabe, Akira Nishimura et al. • Journal of Pharmacological Sciences (2013)

Abstract.: Nitric oxide (NO) induces cytotoxicity in neuronal and glial cells via activation of the Na+/Ca2+ exchanger (NCX). This study examined the role of the predominant brain-specific NCX splice variant NCX1.5 in NO-induced cytotoxicit...

DOAJ Open Access (DOAJ) DOI: 10.1254/jphs.13012SC

Role of pyroptosis in spinal cord injury and its therapeutic implications

Abdullah Al Mamun, Yanqing Wu, Ilma Monalisa, Chang Jia et al. • Journal of Advanced Research (2021)

Background: Currently, spinal cord injury (SCI) is a pathological incident that triggers several neuropathological conditions, leading to the initiation of neuronal damage with several pro-inflammatory mediators' release. However, pyroptosi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jare.2020.08.004

Fumaric acid regulates morphine tolerance in bone cancer pain through spinal MrgC receptor modulation

Sijie Liu, Minghao Tang, Jing Zhao, Lulu Zhang et al. • Pakistan Journal of Pharmaceutical Sciences (2026)

Background: Bone cancer pain (BCP) represents a debilitating complication that profoundly impacts patient quality of life and predisposes to psychological comorbidities, including depression and anxiety. Objectives: To investigate the effec...

DOAJ Open Access (DOAJ) DOI: 10.36721/PJPS.2026.39.8.233.1

Enteric Coating Enhances the Biopharmaceutical Performance of a Silica–Lipid Formulation of Abiraterone Acetate

Ali Taheri, Ruba Almasri, Anthony Wignall, Felicia Feltrin et al. • Pharmaceutics (2025)

Background/Objectives: Lipid-based formulations are widely used to enhance the oral bioavailability of poorly water-soluble drugs. However, for weakly basic drugs with higher solubility under acidic conditions, precipitation and recrystalli...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics17101289

INTERAÇÕES PLANTA MEDICINAL X MEDICAMENTO CONVENCIONAL NO TRATAMENTO DA HIPERTENSÃO ARTERIAL

Júlia Beatriz Pereira SOUZA, Fábia Jéssica Batista ATALIBA, Danielly Albuquerque da COSTA, Andrezza Duarte FARIAS • Infarma: Pharmaceutical Sciences (2017)

A hipertensão arterial sistêmica, dentre as doenças crônicas, apresenta-se como um dos problemas de saúde de maior magnitude na atualidade, sendo uma das principais causas de morbidade e mortalidade cardiovascular no Brasil. Seu tratamento ...

DOAJ Open Access (DOAJ) DOI: 10.14450/2318-9312.v29.e2.a2017.pp90-99

Comparison of Vitamin B1 (Thiamin hydrochloride) Level in Brown Rice (Oryza nivara S.D.Sharma & Shastry) and Cooked Brown Rice by Alkalimetry Methods

Emerita Dyah Ayu Purwita Sari, Hendra Budiman, Anita Agustina Styawan, Choiril Hana Mustofa • Journal of Food and Pharmaceutical Sciences (2025)

Brown rice (Oryza nivara S.D.Sharma & Shastry) is a rice variety that belongs to the Graminae family. Brown rice contains vitamins A, B, C, Zn and B complex. Vitamin B1 is one type of vitamin that is not stable. Its stability is influenced ...

DOAJ Open Access (DOAJ) DOI: 10.22146/jfps.17037

Modified Riceberry rice extract suppresses melanogenesis-associated cell differentiation through tyrosinase-mediated MITF downregulation on B16 cells and in vivo zebrafish embryos

Teerapat Rodboon, Sasithorn Sirilun, Seiji Okada, Ryusho Kariya et al. • Research in Pharmaceutical Sciences (2020)

Background and purpose: Excessive melanin production caused by overactive tyrosinase (TYR) enzyme results in several dermatological problems. The TYR inhibitor, derived from metabolite changes during fermentation, has been well recognized f...

DOAJ Open Access (DOAJ) DOI: 10.4103/1735-5362.297852

Palladium-Catalyzed Stereoselective Construction of 1,3-Stereocenters Displaying Axial and Central Chirality via Asymmetric Alkylations

Aiqi Xue, Xingfu Wei, Yue Huang, Jingping Qu et al. • Molecules (2023)

The concurrent construction of 1,3-stereocenters remains a challenge. Herein, we report the development of stereoselective union of a point chiral center with allenyl axial chirality in 1,3-position by Pd-catalyzed asymmetric allenylic alky...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28072927

Surface-Modified Nanocellulose for Application in Biomedical Engineering and Nanomedicine: A Review

Tortorella S, Vetri Buratti V, Maturi M, Sambri L et al. • International Journal of Nanomedicine (2020)

Silvia Tortorella, Veronica Vetri Buratti, Mirko Maturi, Letizia Sambri, Mauro Comes Franchini, Erica Locatelli Department of Industrial Chemistry “Toso Montanari”, Alma Mater Studiorum – University of Bologna, Bologna 401...

DOAJ Open Access (DOAJ)

Characterization of low-nitrogen quantum diamond for pulsed magnetometry applications

Jiashen Tang, Jiashen Tang, Connor A. Roncaioli, Andrew M. Edmonds et al. • Frontiers in Quantum Science and Technology (2025)

Ensembles of nitrogen-vacancy (NV) centers in diamond are versatile quantum sensors with broad applications in the physical and life sciences. The concentration of neutral substitutional nitrogen ([Ns0]) strongly influences NV electronic sp...

DOAJ Open Access (DOAJ) DOI: 10.3389/frqst.2025.1701548

Synthesis of ultra‐high molecular weight core cross‐linked star (CCS) polymer using high molecular weight spherical nanoparticles and arm‐first method

Guangyao Liu, Yongqi Yang, Chao Zheng, Xiaoqun Cao • Nano Select (2022)

Abstract P (N,N‐Dimethylacrylamide) ‐b‐P (2‐methoxyethyl acrylate) (PDMA‐b‐PMEA) and Poly (poly (ethylene glycol) methyl ether methacrylate) ‐b‐P (2‐methoxyethyl acrylate) (PPEGMA‐b‐PMEA) di‐block copolymer nanoparticles are prepared by RAF...

DOAJ Open Access (DOAJ) DOI: 10.1002/nano.202100216

Modulation Instability and Abundant Exact Solitons to the Fractional Mathematical Physics Model Through Two Distinct Methods

Abdulaziz Khalid Alsharidi, Ahmet Bekir • Axioms (2025)

The paper consists of various types of wave solutions for the truncated M-fractional Bateman–Burgers equation, a significant mathematical physics equation. This model describes the nonlinear waves and solitons in different physical fields s...

DOAJ Open Access (DOAJ) DOI: 10.3390/axioms14080617

Developing an Interferogram-Based Module with Machine Learning for Maintaining Leveling of Glass Substrates

Syuan-Cheng Chang, Chung-Ping Chang, Yung-Cheng Wang, Chi-Chieh Chu • Machines (2023)

In this research, we propose a method that utilizes machine learning to maintain the parallelism of the resonant cavity in a Fabry–Perot interferometer designed specifically for glass substrates. Based on the optical principle and theory, w...

DOAJ Open Access (DOAJ) DOI: 10.3390/machines11060668

Controlled Plasmonic Coupling in Silver Nanoplate Dimers for Enhanced Plasmonic Sensing

Lucrezia Catanzaro, Marcello Condorelli, Mario Pulvirenti, Luisa D’urso et al. • Nanomaterials (2026)

Noble metal nanostructures provide versatile platforms for light manipulation through localized surface plasmon resonances (LSPRs). Among them, triangular silver nanoplates (AgNPTs) exhibit strong field-enhancement and spectral tunability, ...

DOAJ Open Access (DOAJ) DOI: 10.3390/nano16080486

Ultra-Bend-Resistant 4-Core Simplex Cable Used for Short-Reach Dense Spatial Division Multiplexing Optical Transmission

Zelin Zhang, Yu Qin, Jie Zhu, Caoyuan Wang et al. • Micromachines (2024)

We optimized and fabricated an ultra-bend-resistant 4-core simplex cable (SXC) employing 4-core multicore fiber (MCF) suitable for short-reach dense spatial division multiplexing (DSDM) optical transmission in the O-band. The characteristic...

DOAJ Open Access (DOAJ) DOI: 10.3390/mi15010108