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Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

Sarah L. Baines, Kathryn E. Holt, Mark B. Schultz, Torsten Seemann et al. • mBio (2015)

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

DOAJ Open Access (DOAJ) DOI: 10.1128/mBio.00080-15

Antibacterial and antioxidant effects of Punicalagin extracts from Punica granatum peels

Saidakhon T. Islamova, Moxira A. Nazarova, Aktam U. Burkhanov, Fayzulla Khamraev et al. • Caspian Journal of Environmental Sciences (2025)

The growing recognition of the health-promoting potential of compounds derived from natural sources, particularly those exhibiting antimicrobial and antioxidant activities, has resulted in a surge of research publications dedicated to explo...

DOAJ Open Access (DOAJ) DOI: 10.22124/cjes.2025.8570

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Raife Dilek Turan, Cihan Tastan, Derya Dilek Kancagi, Bulut Yurtsever et al. • Scientific Reports (2021)

Abstract The SARS-CoV-2 virus caused the most severe pandemic around the world, and vaccine development for urgent use became a crucial issue. Inactivated virus formulated vaccines such as Hepatitis A and smallpox proved to be reliable appr...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-95086-4

Formation and stability of oil-in-water nanoemulsions containing rice bran oil: <it>in vitro </it>and <it>in vivo </it>assessments

Rocha-Filho Pedro A, Oliveira Gustavo C, Viera Gisely S, Bortoloto Josiane et al. • Journal of Nanobiotechnology (2011)

Abstract Background Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing prod...

DOAJ Open Access (DOAJ) DOI: 10.1186/1477-3155-9-44

CD36‐Binding Amphiphilic Nanoparticles for Attenuation of α‐Synuclein‐Induced Microglial Activation

Nanxia Zhao, Nicola L. Francis, Shuang Song, Vladyslav Kholodovych et al. • Advanced NanoBiomed Research (2022)

Neuroinflammation is one of the hallmarks contributing to Parkinson's disease (PD) pathology, where microglial activation occurs as one of the earliest events, triggered by extracellular α‐synuclein (aSYN) binding to the cluster of differen...

DOAJ Open Access (DOAJ) DOI: 10.1002/anbr.202100120

Peptide-functionalized periodic mesoporous silica nanoparticles for monocyte-specific TET3 Silencing enhance cardiac repair after acute myocardial infarction

Hao Jin, Jiandong Ding, Xiaoguo Zhang, Shouquan Cheng et al. • Journal of Nanobiotechnology (2025)

Abstract Modulating the balance between pro- and anti-inflammatory monocyte subsets holds therapeutic promise in acute myocardial infarction (AMI); however, effective and selective strategies are still lacking. In this study, we are the fir...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03782-4

Bioremediation of Persistent Organic Pollutant—Oxybenzone with <i>Pleurotus djamor</i>

Agata Kryczyk-Poprawa, Wojciech Baran, Katarzyna Sułkowska-Ziaja, Katarzyna Kała et al. • Applied Sciences (2025)

Oxybenzone, a common sunscreen ingredient, has been widely detected in various environmental matrices, posing significant ecological and health risks. The present study demonstrates, for the first time, the capacity of Pleurotus djamor to d...

DOAJ Open Access (DOAJ) DOI: 10.3390/app15094707

The antibiogram of Pus cultures in Federal Tertiary Care Hospital, Islamabad and its utility in antimicrobial stewardshipThe antibiogram of pus cultures in federal tertiary care hospital, Islamabad and its utility in antimicrobial stewardship

Farhan Kursheed, Asraar Tabassum, Umme Farwa, Samia Wazir et al. • Iranian Journal of Microbiology (2024)

Background and Objectives: Antimicrobial resistance has emerged as a significant global health threat. Infections caused by Multi Drug-Resistant (MDR) bacteria pose formidable challenges in terms of treatment options and patient outcomes. P...

DOAJ Open Access (DOAJ) DOI: 10.18502/ijm.v16i1.14871

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Mitra Ansari, Moslem Esmati, Seyed khalil Rashidi, Shahram Rafie et al. • International Journal of Molecular and Cellular Medicine (2025)

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

DOAJ Open Access (DOAJ)

Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia

Chih-Hsiang Yu, Ya-Hsuan Chang, Der-Shiun Wang, Shiann-Tarng Jou et al. • Scientific Reports (2023)

Abstract Mercaptopurine intolerance is an adverse effect of mercaptopurine administration in pediatric patients with acute lymphoblastic leukemia (ALL). NUDT15 variants have emerged as major determinants of mercaptopurine intolerance, espec...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-27720-2

Isolation, characterization, and genomic analysis of a novel phage WSPA with lytic activity against Serratia marcescens

Lijuan Li, Kunkun Li, Yu Mi, Xiumei Wu et al. • Microbiology Spectrum (2025)

ABSTRACT Serratia marcescens is an established pathogen implicated in hospital-acquired infections and is notorious for its propensity to form biofilms on medical devices, leading to persistent environmental contamination and increased infe...

DOAJ Open Access (DOAJ) DOI: 10.1128/spectrum.02716-24

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines (2026)

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines14102234

Distribution of Soil Extracellular Enzymatic, Microbial, and Biological Functions in the C and N-Cycle Pathways Along a Forest Altitudinal Gradient

Mohammad Bayranvand, Mohammad Bayranvand, Moslem Akbarinia, Gholamreza Salehi Jouzani et al. • Frontiers in Microbiology (2021)

The diverse chemical, biological, and microbial properties of litter and organic matter (OM) in forest soil along an altitudinal gradient are potentially important for nutrient cycling. In the present study, we sought to evaluate soil chemi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2021.660603

Curcumin: Reintroduced Therapeutic Agent from Traditional Medicine for Alcoholic Liver Disease

Hamid Reza Rahimi, Mahmoud Reza Jaafari, Amir Hooshang Mohammadpour, Khalil Abnous et al. • Asia Pacific Journal of Medical Toxicology (2015)

Alcoholic liver disease (ALD) is the main cause of chronic liver disease across the world and can lead to fibrosis and cirrhosis. The etiopathogenesis of ALD is related to ethanol-induced oxidative stress, glutathione reduction, abnormal me...

DOAJ Open Access (DOAJ) DOI: 10.22038/apjmt.2015.3983

Pharmacological significance of MitoQ in ameliorating mitochondria-related diseases

Lateef Adegboyega Sulaimon, Lukman Olalekan Afolabi, Rahmat Adetutu Adisa, Akinrinade George Ayankojo et al. • Advances in Redox Research (2022)

The Mitochondria is a critical sub-cellular organelle that plays an integral part in a normal cellular process. Besides ATP production, the mitochondria participate in various key cellular processes such as cell signaling, epigenetic regula...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.arres.2022.100037

Photoluminescent Nanomaterials for Medical Biotechnology

Evgenii L. Guryev, Samah Shanwar, Andrei V. Zvyagin, Sergey Mikhailovich Deyev et al. • Acta Naturae (2021)

Creation of various photoluminescent nanomaterials has significantly expanded the arsenal of approaches used in modern biomedicine. Their unique photophysical properties can significantly improve the sensitivity and specificity of diagnosti...

OPENALEX cc-by DOI: https://doi.org/10.32607/actanaturae.11180 PMC: 8327149

Medical Biotechnology Innovation in India

P. Omkar Nadh • Routledge eBooks (2022)

This book examines the medical biotechnology industry in India through the lens of a critical political economy. It discusses the sharp trajectory of growth in the biotechnology business and the state of investments, subsidies, and patents ...

OPENALEX DOI: https://doi.org/10.4324/9781003292104

Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy

Yi Shuai, Bo Chen, Tao Jiang, Lei Zhu et al. • Journal of Nanobiotechnology (2025)

Abstract Background Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to va...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03745-9