Academic Articles & Research Papers

Necroptosis and Neuroinflammation in Retinal Degeneration

Necroptosis mediates the chronic inflammatory phenotype in neurodegeneration. Receptor-interacting protein kinase (RIPK) plays a pivotal role in the induction of necroptosis in various cell types, including microglia, and it is implicated i...

The Immunomodulatory and Anti-Inflammatory Effect of Curcumin on Immune Cell Populations, Cytokines, and In Vivo Models of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a widespread chronic autoimmune disorder affecting the joints, causing irreversible cartilage, synovium, and bone degradation. During the course of the disease, many immune and joint cells are activated, causing...

Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress

Saba Naqvi1, Mohammad Samim2, MZ Abdin3, Farhan Jalees Ahmed4, AN Maitra5, CK Prashant6, Amit K Dinda61Faculty of Engineering and Interdisciplinary Sciences, 2Department of Chemistry, 3Department of Biotechnology, Faculty of Science, 4Depar...

Flexibility-powered Pickering emulsion enhances mucus permeability to alleviate ulcerative colitis

Abstract The physicochemical properties of oral drug delivery carriers significantly influence their interactions with the intestinal barrier, which, in turn, affect their in vivo fate and therapeutic efficacy. As a delivery system with a h...

Editorial: Application of network-theoretic approaches in biology

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

The devastating effects and incurable nature of hereditary and sporadic retinal diseases such as Stargardt disease, age-related macular degeneration or retinitis pigmentosa urgently require the development of new therapeutic strategies. Add...

Molecular basis of pathogenesis of emerging viruses infecting aquatic animals

Aquatic vertebrates are very abundant in the world, and they are of tremendous importance in providing global food security and nutrition. However, emergent and resurgent viruses, such as ranavirus (e.g., Rana grylio virus, RGV and Andriasd...

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

Plants, with their range of pharmacologically active molecules, represent the most promising source for the production of new anticancer drugs and for the formulation of adjuvants in chemotherapy treatments to reduce drug content and/or cou...

Micro-moves in International Relations theory

This article posits empirical and political reasons for recent ‘micro-moves’ in several contemporary debates, and seeks to further develop them in future International Relations studies. As evidenced by growing trends in studies of practice...

ECONOMIC STUDY FOR COST PEST DISEASES OF EGYPTION COTTON BEFORE AND AFTAR BIORATIONAL PEST PROGRAMME

Cotton crop is one of the important crops at the local and international level as well. because various manufactures depend on it. In addition to it's first class among all agricultural exports, where it represents about 25% of the total ...

Integrated crop-livestock-forest systems: a path to improved agro-economic performance in the Brazilian Amazon and Cerrado

Diversified sustainable agricultural systems, such as integrated crop-livestock-forest systems (ICLFs), offer substantial potential for enhancing food production to meet the increasing global demand for agricultural goods while, simultaneou...

AIDS e pauperização: principais conceitos e evidências empíricas AIDS and pauperization: principal concepts and empirical evidence

O artigo discute as estratégias metodológicas que vêm sendo usadas na análise das inter-relações entre a vulnerabilidade ao HIV/AIDS e as desigualdades sociais, o preconceito e a marginalização, ressaltando-se as dificuldades metodológicas ...

Landscape patterns and their spatial associations with ecosystem service balance: Insights from a rapidly urbanizing coastal region of southeastern China

Abstract: Assessing ecosystem service (ES) balance and exploring critical drivers are crucial for landscape management. However, a lack of understanding of the determinants of the ecosystem service supply–demand budget, their spillover effe...

LOCAL COMMUNITY’S ECOLOGICAL KNOWLEDGE IN THE SELECTION OF SHADING TREESFOR TRADITIONAL AGROFORESTRY SYSTEM (NUTMEG “DUSUNG”) IN AMBON

Local ecological knowledge is closely linked to decision-making process for planting tree. The aims of this study are to describe and explain local community’s decision-making process in the selection of shading trees on their lands accordi...

In Vitro Propagation of the Endangered <i>Kosteletzkya pentacarpos</i> (L.) Ledeb: Conservation Applications and Horticultural Prospects

Employing rare or threatened species in ornamental horticulture offers a dual benefit by promoting climate adaptation and enhancing species conservation. Kosteletzkya pentacarpos, an endangered halophytic species, holds potential for introd...

Lipid remodeling enhances heat tolerance in rose via α-linolenic acid and jasmonate accumulation

The rose, often referred to as the queen of flowers, is one of the four primary cut flowers; however, its growth is susceptible to high-temperature stress. Furthermore, with the advent of global warming, extreme high temperatures are becomi...

Genome‐wide association studies of fruit quality traits in jujube germplasm collections using genotyping‐by‐sequencing

Abstract Chinese jujube (Ziziphus jujuba Mill.) is an important fruit crop and harbors many highly diverse traits of potential economic importance. Fruit size, stone size, and fruit cracking have an important influence on the commercial val...

Evaluation of the performance of several cultivars of bean (Vicia faba L.) for yield and its components under three different cultivation distances

This study was conducted in the center of Kirkuk governorate in the farms of a farmer for the agricultural season 2020/2021. The study included two factors, the first is the distance between the meadows, where the following distances were u...

Evaluation of the developmental toxicity of 2-phenoxyethanol and clove oil anaesthetics using the Frog Embryo Teratogenesis Assay: Xenopus (FETAX)

The developmental toxicity of two anaesthetics, 2-phenoxyethanol and clove oil, used in aquaculture was evaluated using the Frog Embryo Teratogenesis Assay: Xenopus (FETAX) and the results were compared to outcomes in fish. Xenopus laevis e...

Preliminary screening of biostimulative effects of Göemar BM-86 on eggplant cultivars grown under field conditions in Poland

Seaweed extracts are widely used in agriculture as ecological focus substances applied to improve crop growth and quality. One of the primary benefits they bring is increased effectiveness of fruit setting as well as improved stress toleran...