Academic Articles & Research Papers

Progressive suppression of regulated cell death defines terminal macrophage states in liver cirrhosis

Background Macrophages are central regulators of liver immunity and fibrosis; Recent single-cell studies have characterized macrophage heterogeneity in cirrhosis; however, how regulated cell death programs shape their functional transitions...

Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications

Yusi Liu, Xue Song, Moli Wu, Jiao Wu, Jia Liu Liaoning Laboratory of Cancer Genetics and Epigenetics and Department of Cell Biology, College of Basic Medical Sciences, Dalian Medical University, Dalian, People’s Republic of ChinaCorre...

Editorial: The neurogenetics of brain wiring

A Comparative Analysis of the Chloroplast Genomes of Four Polygonum Medicinal Plants

Polygonum is a generalized genus of the Polygonaceae family that includes various herbaceous plants. In order to provide aid in understanding the evolutionary and phylogenetic relationship in Polygonum at the chloroplast (cp) genome-scale l...

Causal relationship between genetic-predicted uric acid and cervical cancer risk: evidence for nutritional intervention on cervical cancer prevention

IntroductionThe relationship between serum uric acid (SUA) and cervical cancer is inconclusive. This study aims to investigate the causal relationship between SUA levels and cervical cancer incidence, and to evaluate the potential role of n...

Effectiveness of Ultrasound Imaging in Assessing the Palpation Skills of Rotating Physicians

As an important means of physical examination, palpation is usually limited to the physical examination before surgery and used as an auxiliary method for disease diagnosis in the field of surgery. In practice, palpation is also used in eve...

CRISPR/Cas9 for hepatitis B virus infection treatment

Abstract Hepatitis B virus (HBV) infection remains a global health challenge. Despite the availability of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular carcinoma. Current drug therapies inhibi...

Long-term farmland abandonments remarkably increased the phytolith carbon sequestration in soil

Abstract Background Phytolith-occluded organic carbon (PhytOC) is an important mechanism of long-term stable carbon sinks in terrestrial ecosystems. Farmland abandonment is a widespread land use change in the process of urbanization and ind...

The impact of intelligent technology progress on skill matching in labor market—evidence from China

Through mathematical deduction, this paper reveals the impact of intelligent technology progress on skill matching in labor market. This paper constructs a provincial-level comprehensive index of industrial intelligence from three dimension...

Energy Internet Evaluation Index System under the Zero Carbon Goal

At present, the zero-carbon goal has become the common choice of all the world. Driven by the zero-carbon goal, energy system in China will develop to be cleaner and cleaner. In this situation, Energy Internet has become the future developm...

Developing European policy on xenotransplantation: instructive findings from the first representative UK sample survey on attitudes and views on animal to human transplants

Recent landmark advances, particularly those related to gene-editing technology and the pioneering pig-to-human transplants currently underway in the USA and China, mean that xenotransplantation (XTx) may become a realistic option for patie...

Socioeconomic inequalities in effective service coverage for reproductive, maternal, newborn, and child health: a comparative analysis of 39 low-income and middle-income countries

Background: Reducing socioeconomic inequalities in access to good quality health care is key for countries to achieve Universal Health Coverage. This study aims to assess socioeconomic inequalities in effective coverage of reproductive, mat...

Development of the Cooperative Intelligent Transport System in Thailand: A Prospective Approach

Smart mobility is becoming an alternative technology of transportation development for today and the future. Thailand has applied the intelligent transport system (ITS) to improve traffic and transport services. The success of the project i...

Acupuncture versus sham acupuncture and usual care for Antiandrogen-Induced hot fLashes in prostate cancer (AVAIL): study protocol for a randomized clinical trial

Abstract Background Hot flashes are the common and debilitating symptom among prostate cancer (PCa) patients undergoing androgen deprivation therapy (ADT). Strong evidence from multiple rigorously designed studies indicated that pharmacolog...

Estimating Chinese bilateral aid for health: an analysis of AidData’s Global Chinese Official Finance Dataset Version 2.0

Background Although it is difficult to quantify, previous estimates suggested that China’s global health aid has increased sharply since the early 2000s. Unlike many donors, China has no official aid reporting obligations, nor does it volun...

Evaluating the effect of comprehensive land consolidation on spatial reconstruction of rural production, living, and ecological spaces

China’s long-standing dual-track institutions, which differentiate between urban and rural areas, have prioritized urban development, exacerbating the urban–rural divide and contributing to the ongoing decline of rural regions. In response,...

A Web-Based Honeypot in IPv6 to Enhance Security

IPv6 is a next-generation IP protocol that replaces IPv4. It not only expands the number of network address resources but also solves the problem of multiple access devices connected to the Internet. While IPv6 has brought excellent conveni...

Effect of the mHealth-supported Healthy Future programme delivered by community health workers on maternal and child health in rural China: study protocol for a cluster randomised controlled trial

Introduction Millions of young rural children in China still suffer from poor health and malnutrition, partly due to a lack of knowledge about optimal perinatal and child care among rural mothers and caregivers. Meanwhile, there is an urgen...

Feasibility and priority strategies for diabetes prevention and control in Chinese demonstration areas

Background Diabetes is a leading global public health challenge with 537 million cases worldwide in 2021 and significant economic and societal burdens. Despite global initiatives, feasibility constraints limit widespread implementation of d...

Innovations for Interpretability, Flexibility, and Sustainability in Intelligent Machinery and Industry 4.0

Three levels, namely the device level, the connection level, and the systems management level, are frequently used to conceptualize intelligent machinery and Industry 4 [...]...