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Research progress of automated ultrasonic imaging detection technology for complex aircraft components

CHEN Yao, XIONG Zhenghui, LUO Junwei, WANG Hanyang et al. • Journal of Aeronautical Materials (2025)

Traditional ultrasonic automated non-destructive testing is a great challenge in the inspection of aviation components with complex surfaces. Complex surfaces can interfere with the formation of the focus in the sound beam,and the waveform ...

DOAJ Open Access (DOAJ) DOI: 10.11868/j.issn.1005-5053.2024.000173

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali et al. • Cell Reports (2018)

Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compar...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.celrep.2018.10.070

Sex- and age-specific effects of fat distribution on bone mineral density

Xiao Lin, Jun-Jie Yang, Bei Huang, Peng-Xin Wang et al. • Experimental Gerontology (2026)

Background: BMI cannot distinguish fat distribution and may mask the true effects of different fat depots on bone mineral density (BMD). To investigate sex- and age-specific associations between fat distribution and BMD and its mediating ro...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2026.113301

A nationwide study on immunosenescence biomarkers profile in older adults: ELSI-Brazil

Maria Luiza Lima-Silva, Karen Cecília Lima Torres, Juliana Vaz de Melo Mambrini, Nathalia Coimbra Brot et al. • Experimental Gerontology (2024)

Immunosenescence is a phenomenon caused by changes in the immune system, and part of these changes involves an increase in circulating immunological biomarkers, a process known as “Inflammaging.” Inflammaging can be associated with many dis...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2024.112433

Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology (2026)

Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2026.113057

Equipment in Senior Gyms: Influence on the Behavior of Blood Pressure and Heart Rate of Elderlies

Sillas Oliveira Leonel Júnior, Mateus Dias Antunes, Ramon Gustavo de Moraes Ovando, Ana Paula Serra de Araújo et al. • Geriatrics, Gerontology and Aging (2024)

OBJECTIVE: To analyze the behavior of blood pressure and heart rate in elderly people practicing physical exercises in Maringá, Paraná, Brazil. METHODS: 70 elderly volunteers were evaluated, 41 women and 29 men, with a mean age of 67.2 ± 6....

DOAJ Open Access (DOAJ) DOI: 10.5327/Z2447-211520171700042

Rare genetic diseases associated with G-quadruplex-induced replication stress

Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology (2026)

Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-026-09966-4

Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu et al. • Experimental Gerontology (2024)

The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cel...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2024.112633

Effectiveness of music-based interventions in acute care settings for people living with dementia to reduce anxiety and enhance the care experience: A systematic review.

Victoria McArthur, Susan Everington, Martyn Patel • Archives of Gerontology and Geriatrics Plus (2024)

Introduction: Dementia is a global health priority, with an increasing percentage of overall hospital bed days occupied by people with dementia (PWD). This combined with increased demand and availability of complex scanning means that there...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2024.100087

Impact of age-friendly living environment and intrinsic capacity on functional ability in older adults: a cross-sectional study

Yi-Shan Jiang, Hong Shi, Yu-Ting Kang, Ji Shen et al. • BMC Geriatrics (2023)

Abstract Background The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-04089-5

Creating Exercise Spaces in Parks for Older Adults With Fitness, Rehabilitation, and Play Elements: A Review and Perspective

Janet Lok Chun Lee, Rainbow Tin Hung Ho • Gerontology and Geriatric Medicine (2022)

Parks usually create a protective playground space for children to perform physical activity like jumping, running, and climbing. Specific spaces have rarely been created for older adults to perform physical activity in public parks. Now th...

DOAJ Open Access (DOAJ) DOI: 10.1177/23337214221083404

Neuronal-Derived EV Biomarkers Track Cognitive Decline in Alzheimer’s Disease

Erden Eren, Jeannie-Marie Leoutsakos, Juan Troncoso, Constantine G. Lyketsos et al. • Cells (2022)

The hallmarks of Alzheimer’s disease (AD) pathology are senile plaques containing amyloid-beta (Aβ) and neurofibrillary tangles containing hyperphosphorylated tau. Additional pathologies often co-exist, whereas multiple pathogenic mechanism...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells11030436

Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease

Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen et al. • BMC Geriatrics (2025)

Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vul...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-025-05721-2

Predictivity of bioimpedance phase angle for incident disability in older adults

Kazuki Uemura, Takehiko Doi, Kota Tsutsumimoto, Sho Nakakubo et al. • Journal of Cachexia, Sarcopenia and Muscle (2020)

Abstract Background Bioelectrical impedance analysis (BIA)‐derived phase angle is expected to be an efficient prognostic marker of health adverse events with aging as an alternative of muscle mass. We aimed to examine the predictive ability...

DOAJ Open Access (DOAJ) DOI: 10.1002/jcsm.12492

Efeito do Exercício na Funcionalidade, na Depressão e na dor de Idosos Institucionalizados

Alessandra da Silva Oliveira, Claudia Teixeira-Arroyo • Geriatrics, Gerontology and Aging (2024)

Objetivo: Verifi car o efeito de um programa de exercícios físicos funcionais, associados ao componente lúdico, nos sintomas depressivos, na capacidade de realização das atividades da vida diária (AVD) e nos sintomas de dor de idosos instit...

DOAJ Open Access (DOAJ)

Comparative efficacy of exercise interventions for cognitive health in older adults: A network meta-analysis

Jinhao Zhang, Wei Ye, Wang Li, Fan Zhang et al. • Experimental Gerontology (2025)

Background: Previous studies have consistently demonstrated that exercise mitigates cognitive decline in older adults. However, the most effective types of exercise, along with optimal frequency and duration of interventions, remain inadequ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112768

Fluidity in filial piety: twenty-year associations of living arrangements on depression and life satisfaction and across chronic diseases among older adults in rural China

Jin Guo, Andrew Wister, Barbara Mitchell, Merril Silverstein et al. • BMC Geriatrics (2026)

Abstract Objectives Based on defamilization, individualization, and contingent intergenerational solidarity theories, this study developed a cultural defamilization framework. Longitudinal data were used to explore changes in the associatio...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-026-07449-z

Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases

Tetsuro Tago, Jun Toyohara • Molecules (2018)

Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules23020300