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Peptide-functionalized periodic mesoporous silica nanoparticles for monocyte-specific TET3 Silencing enhance cardiac repair after acute myocardial infarction

Hao Jin, Jiandong Ding, Xiaoguo Zhang, Shouquan Cheng et al. • Journal of Nanobiotechnology (2025)

Abstract Modulating the balance between pro- and anti-inflammatory monocyte subsets holds therapeutic promise in acute myocardial infarction (AMI); however, effective and selective strategies are still lacking. In this study, we are the fir...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03782-4

Optimally biosynthesized, PEGylated gold nanoparticles functionalized with quercetin and camptothecin enhance potential anti-inflammatory, anti-cancer and anti-angiogenic activities

Priyadarshani S. Sadalage, Reshma V. Patil, Darshana V. Havaldar, Shruti S. Gavade et al. • Journal of Nanobiotechnology (2021)

Abstract Background The development of nano delivery systems is rapidly emerging area of nanotechnology applications where nanomaterials (NMs) are employed to deliver therapeutic agents to specific site in a controlled manner. To accomplish...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-021-00836-1

Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians

Audre Preena Maria Sundar Raj, Gayathri Selvakumar, James Clement, George M. Church et al. • Human Genomics (2025)

Abstract Aging, a complex biological process, entails sequential changes in organisms that elevate the risk of frailty, disease, and mortality, affecting individuals at the level of cellular, organ, and organism. This process is influenced ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40246-025-00772-3

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Mitra Ansari, Moslem Esmati, Seyed khalil Rashidi, Shahram Rafie et al. • International Journal of Molecular and Cellular Medicine (2025)

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

DOAJ Open Access (DOAJ)

Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms

Xiao Wang, Wenxuan Shi, Yu Jin, Zhuoyuan Li et al. • Journal of Nanobiotechnology (2025)

Abstract The escalating hazards posed by bacterial infections underscore the imperative for pioneering advancements in next-generation antibacterial modalities and treatments. Present therapeutic methodologies are frequently impeded by the ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03126-2

Current Evidence on Gene-Based and Epigenetic Therapeutic, Diagnostic, and Prognostic Strategies in Epithelial-Derived Carcinomas: A Scoping Review

Joshua George Thomas, Mohammed Ayyub, Lovely M. Annamma, Prathibha Prasad et al. • Biomedicines (2026)

Background: Epithelial-derived carcinomas exhibit genomic instability due to genetic mutation and epigenetic dysregulation. Mechanisms such as DNA methylation, histone modifications, and noncoding RNA regulation may lead to tumor progressio...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines14102234

Lipidomic Analysis of Caenorhabditis elegans Embryos

Hung-Chi Yang, Cheng-Yu Hung, Yi-Yun Pan, Szecheng Lo et al. • Bio-Protocol (2017)

Metabolomic is an emerging field of system biology. Lipidomic, a branch of metabolomic, aims to characterize lipophilic metabolites in biological systems. Caenorhabditis elegans (C. elegans) is a genetically tractable and versatile animal m...

DOAJ Open Access (DOAJ) DOI: 10.21769/BioProtoc.2554

Economic Considerations in Medical Biotechnology

Eugene Mick Kolassa, Tushar B. Padwal • Springer eBooks (2013)

The biotechnology revolution has coincided with another revolution in health care: the emergence of finance and economics as major issues in the use and success of new medical technologies. Health care finance has become a major social issu...

OPENALEX DOI: https://doi.org/10.1007/978-1-4614-6486-0_10

Medical biotechnology

Findlay, Joshua • University of Salford Institutional Repository (University of Salford) (2016)

Resistance to entering the UK government's modern slavery victim identification mechanism is widespread and part of normal practices of state evasion that shape the lives of large numbers of insufficiently documented people.This article pro...

OPENALEX cc-by

Medical Biotechnology Innovation in India

P. Omkar Nadh • Routledge eBooks (2022)

This book examines the medical biotechnology industry in India through the lens of a critical political economy. It discusses the sharp trajectory of growth in the biotechnology business and the state of investments, subsidies, and patents ...

OPENALEX DOI: https://doi.org/10.4324/9781003292104

CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy

Xinyue Gao, Feichang Liu, Bo Zhang, Tianyi Ren et al. • Cell Death and Disease (2025)

Abstract Cell division cycle 25 (CDC25) phosphatases serve as crucial regulators of cell cycle phase transitions and essential components of the checkpoint machinery involved in DNA damage response. Emerging evidence indicates the oncogenic...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41419-025-07598-w

Targeting ferroptosis to rescue osteogenic differentiation in BRONJ-affected jawbone mesenchymal stem cells: the role of miR-145-3p and exosome-mediated therapy

Yi Shuai, Bo Chen, Tao Jiang, Lei Zhu et al. • Journal of Nanobiotechnology (2025)

Abstract Background Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe, therapy-refractory condition driven by ferroptotic disruption of jawbone-derived mesenchymal stem cells (MSCs) biology. We dissect this mechanism to va...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12951-025-03745-9

Expression of Recombinant Human Amelogenin in Iranian Lizard Leishmania and Its Biological Function Assay

Zahra YADEGARI, Mojgan BANDEHPOUR, Bahram KAZEMI, Khojasteh SHARIFI-SARASIABI • Iranian Journal of Public Health (2015)

Background: Amelogenins are the major components of enamel matrix proteins. Enamel matrix derivatives (EMD) can be used in periodontal diseases to regenerate periodontal tissues. The main aim of this study was to evaluate ex-pression of ful...

DOAJ Open Access (DOAJ)