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Graphene Oxide and Reduced Derivatives, as Powder or Film Scaffolds, Differentially Promote Dopaminergic Neuron Differentiation and Survival

Noela Rodriguez-Losada, Noela Rodriguez-Losada, Rune Wendelbob, M. Carmen Ocaña et al. • Frontiers in Neuroscience (2020)

Emerging scaffold structures made of carbon nanomaterials, such as graphene oxide (GO) have shown efficient bioconjugation with common biomolecules. Previous studies described that GO promotes the differentiation of neural stem cells and ma...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2020.570409

Sexual Dimorphism in Growth Rate and Gene Expression Throughout Immature Development in Wild Type Chrysomya rufifacies (Diptera: Calliphoridae) Macquart

Meaghan L. Pimsler, Meaghan L. Pimsler, Meaghan L. Pimsler, Carl E. Hjelmen et al. • Frontiers in Ecology and Evolution (2021)

Reliability of forensic entomology analyses to produce relevant information to a given case requires an understanding of the underlying arthropod population(s) of interest and the factors contributing to variability. Common traits for analy...

DOAJ Open Access (DOAJ) DOI: 10.3389/fevo.2021.696638

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang et al. • Nature Communications (2021)

The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery....

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-24131-7

Green synthesis, characterization and functional validation of bio-transformed selenium nanoparticles

S. Vasanthakumar, M. Manikandan, Muthu Arumugam • Biochemistry and Biophysics Reports (2024)

Selenium, an essential micronutrient with potent anticancer and antioxidant properties, the inorganic form of selenium is highly toxic, while organic and elemental nanoforms are more bioavailable and less toxic and have gained attention owi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.bbrep.2024.101760

Involvement of two uptake mechanisms of gold and iron oxide nanoparticles in a co-exposure scenario using mouse macrophages

Dimitri Vanhecke, Dagmar A. Kuhn, Dorleta Jimenez de Aberasturi, Sandor Balog et al. • Beilstein Journal of Nanotechnology (2017)

Little is known about the simultaneous uptake of different engineered nanoparticle types, as it can be expected in our daily life. In order to test such co-exposure effects, murine macrophages (J774A.1 cell line) were incubated with gold (A...

DOAJ Open Access (DOAJ) DOI: 10.3762/bjnano.8.239

Paraffinic oil residues after heating as a basis for fuel

Zvereva Elvira, Makarova Anastasiya, Ilyin Nikolay, Ageeva Marina et al. • E3S Web of Conferences (2023)

The possibility of reuse of heavy residues (oily sludge) of low-sulfur, highly paraffinic Mangyshlak oils as a basis for fuel with improved environmental characteristics for engines to marine, river and railway transport, gas turbine and bo...

DOAJ Open Access (DOAJ) DOI: 10.1051/e3sconf/202337604020

Polymer brush in articular cartilage lubrication: Nanoscale modelling and simulation

Nobuhiko Kajinami, Mitsuhiro Matsumoto • Biophysics and Physicobiology (2019)

Human knee joints move smoothly under high load conditions due to articular cartilage and synovial fluid. Much attention is paid to the role of proteoglycans. It is suggested that a part of proteoglycan forms aggregate on the cartilage surf...

DOAJ Open Access (DOAJ) DOI: 10.2142/biophysico.16.0_466

Mechanistic insights into TAM-mediated OMP assembly in Gram-negative bacteria

Qinghua Luo, Xintan Dong, Zhaxi Zerang, Yujiao Chen et al. • Cell Reports (2026)

Summary: The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.celrep.2026.117733

Revisiting Hyaluronan Catabolism in Bacteroides: Pathway Conservation, Overlooked Proteins, and Predictive Accuracy

Martin Sindelar, Anna Kocurkova, Matej Simek, Pavel Roudnicky et al. • MicrobiologyOpen (2026)

ABSTRACT The ability of gut microbes to degrade host‐ and diet‐derived glycans is central to microbiome ecology and host interactions, yet predicting these functions in silico remains challenging. Hyaluronan (HA), a glycosaminoglycan (GAG) ...

DOAJ Open Access (DOAJ) DOI: 10.1002/mbo3.70227

Roles of Rap1 signaling in tumor cell migration and invasion

Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine (2017)

Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...

DOAJ Open Access (DOAJ) DOI: 10.20892/j.issn.2095-3941.2016.0086

Membrane Dysfunction as a Central Mechanism in LRRK2-Associated Parkinson’s Disease: Comparative Analysis of G2019S and I1371V Variants

Khushboo Singh, Roon Banerjee, Chandrakanta Potdar, Anisha Shaw et al. • Cells (2026)

Mutations in leucine-rich repeat kinase 2 (LRRK2) are among the most common genetic causes of Parkinson’s disease (PD), yet substantial heterogeneity exists among pathogenic variants. How mutations in distinct functional domains of LRRK2 di...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells15040342

Dielectric Properties of Phosphatidylcholine Membranes and the Effect of Sugars

Victoria Vitkova, Vesela Yordanova, Galya Staneva, Ognyan Petkov et al. • Membranes (2021)

Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is...

DOAJ Open Access (DOAJ) DOI: 10.3390/membranes11110847

Pairwise Performance Comparison of Docking Scoring Functions: Computational Approach Using InterCriteria Analysis

Maria Angelova, Petko Alov, Ivanka Tsakovska, Dessislava Jereva et al. • Molecules (2025)

Scoring functions are key elements in docking protocols as they approximate the binding affinity of a ligand (usually a small bioactive molecule) by calculating its interaction energy with a biomacromolecule (usually a protein). In this stu...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules30132777

Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway

Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang et al. • Journal of Translational Medicine (2024)

Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-deri...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-024-05257-w

Comparative Analysis of Tools and Approaches for Source Tracking Listeria monocytogenes in a Food Facility Using Whole-Genome Sequence Data

Balamurugan Jagadeesan, Leen Baert, Martin Wiedmann, Renato H. Orsi • Frontiers in Microbiology (2019)

As WGS is increasingly used by food industry to characterize pathogen isolates, users are challenged by the variety of analysis approaches available, ranging from methods that require extensive bioinformatics expertise to commercial softwar...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2019.00947

An integrated analysis of multiple datasets reveals novel gene signatures in human granulosa cells

Xhulio Dhori, Silvia Gioiosa, Stefania Gonfloni • Scientific Data (2024)

Abstract Granulosa cells (GCs) play crucial roles in oocyte maturation. Through gap junctions and extracellular vesicles, they mediate the exchange of molecules such as microRNAs and messenger RNAs. Different ovarian cell types exhibit uniq...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41597-024-03715-0

Cranial ultrasonographic findings in newborns exposed to SARS-CoV-2: a single-centre cross-sectional analysis

Bruna Scalia, Marco Andrea Nicola Saporito, Laura Mauceri, Alessandro Valerio Saporito et al. • Italian Journal of Pediatrics (2024)

Abstract Background SARS-CoV-2’s potential consequences on the developing brain are still unknown. The aim of this study was to describe cranial ultrasonographic (cUS) findings in a population of newborns exposed to SARS-CoV-2 born at San M...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13052-024-01826-3

Assessment of Safety and Probiotic Traits of Enterococcus durans OSY-EGY, Isolated From Egyptian Artisanal Cheese, Using Comparative Genomics and Phenotypic Analyses

Walaa E. Hussein, Walaa E. Hussein, Ahmed G. Abdelhamid, Ahmed G. Abdelhamid et al. • Frontiers in Microbiology (2020)

An Enterococcus durans strain, designated OSY-EGY, was previously isolated from artisanal cheese. In this work, comparative genomic and phenotypic analyses were utilized to assess the safety characteristics and probiotic traits of the bacte...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2020.608314

CD56-Negative Extranodal Natural Killer/T-Cell Lymphoma: A Retrospective Study in 443 Patients Treated by Chemotherapy With or Without Asparaginase

Jing Yang, Pengfei Li, Pengfei Li, Pengfei Li et al. • Frontiers in Immunology (2022)

ObjectiveExtranodal natural killer/T cell lymphoma (NKTCL) is an aggressive EBV-related lymphoma, originating from NK cells or T cells. Previous study demonstrated that CD56 negative NKTCL should be recognized as a distinct subtype. In this...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2022.829366