Academic Articles & Research Papers

MBOAT7-TMC4 rs641738 Is Not Associated With the Risk of Hepatocellular Carcinoma or Persistent Hepatitis B Infection

ObjectiveA hot genetic variant, rs641738 within the membrane-bound O-acyltransferase domain containing 7(MBOAT7) and transmembrane channel-like 4 (TMC4), was recently reported to be associated with several liver diseases. However, the resul...

Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-...

Clinical yarning with Aboriginal and/or Torres Strait Islander peoples—a systematic scoping review of its use and impacts

Abstract Objectives To explore how clinical yarning has been utilised as a health intervention for Aboriginal and/or Torres Strait Islander peoples and if there are any reported impacts yarning might have on health outcomes. Study design Sy...

Effectiveness of Back care education Programme among school children: a systematic review of randomized controlled trials

Abstract Study design Systematic review of Randomised controlled trials. Objectives With the increasing incidence of back pain among children and its untold implications to their future, back education tailored in an effective way would be ...

The clinical effectiveness and cost-effectiveness of gemcitabine for metastatic breast cancer: a systematic review and economic evaluation

Health technology, quality and safety in a learning health system

Health technology quality and safety is an important issue for health informatics (i.e. digital health) professionals. Health technologies have been used to (1) collect data that can be analyzed to improve the quality and safety of healthca...

Barriers and facilitators to utilizing digital health technologies by healthcare professionals

Abstract Digital technologies change the healthcare environment, with several studies suggesting barriers and facilitators to using digital interventions by healthcare professionals (HPs). We consolidated the evidence from existing systemat...

A taxonomy of model structures for economic evaluation of health technologies

Models for the economic evaluation of health technologies provide valuable information to decision makers. The choice of model structure is rarely discussed in published studies and can affect the results produced. Many papers describe good...

Health technology assessment: a framework

In a time where there is growing pressure on healthcare budgets, there is increased scrutiny of new health technologies, their effectiveness, safety and costs.1 It is in this context that Health Technology Assessment (HTA) has become increa...

Health technology innovations

The global pandemic has drastically impacted older adults in numerous ways (e.g., loneliness; age discrimination; mental and physical health; limited access to traditional health care).On the other hand, it may have accelerated the general ...

Health technology assessment in England and Wales

In this study, we describe the current state of the Health Technology Assessment (HTA) system in England and Wales. This system rests on a distinction between assessment and appraisal and has three main strands: researcher-led HTA, the rese...

The Impact of Bio-Based Fertilizer Integration Into Conventional Grassland Fertilization Programmes on Soil Bacterial, Fungal, and Nematode Communities

Phosphorus (P) is an essential plant macro-nutrient applied to soil in agriculture, mainly sourced from non-renewable mined phosphate-rock, of which readily accessible reserves are currently under pressure, while global food demand continue...

From Health Technology Assessment to Health Technology Sustainability

This paper aims to propose a methodological lens to the assessment of technological innovations in healthcare based on the principles of social, economic, and political sustainability. Starting from the consideration of a lack of a unified ...

Health technology assessment

Reports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors.Reviews in Health Tec...

User-Centered Design and Interactive Health Technologies for Patients

Despite recommendations that patients be involved in the design and testing of health technologies, few reports describe how to involve patients in systematic and meaningful ways to ensure that applications are customized to meet their need...

Health technology assessment in mental health services

Mental illnesses have a significant impact on the lives of people not only because of their morbidity but also because of their noticeable impact on economic wellbeing. Out-of-pocket expenditure for mental healthcare services is significant...

Robotic-assisted anatomic anterior cruciate ligament reconstruction: a comparative analysis of modified transtibial and anteromedial portal techniques in cadaveric knees

Introduction: This study employed surgical robot to perform anatomic single-bundle reconstruction using the modified transtibial (TT) technique and anteromedial (AM) portal technique. The purpose was to directly compare tunnel and graft cha...

Editorial Summer 2025

Early childhood education (ECE) lays the foundation for a child's lifelong learning journey. More and more, new insights and understandings of child development are evolving, and concomitantly, new preschool education has seen several excit...

Use of qualitative and mixed methods research in diagnostic technology evaluation and implementation: insights from a systematic review

Abstract Background Development of new diagnostic health technologies is increasing, alongside interest in how they can be implemented into health services. Evaluation of new diagnostic tests has typically consisted of technical and diagnos...

Designing mobile health technology for bipolar disorder

An increasing number of pervasive healthcare systems are being designed, that allow people to monitor and get feedback on their health and wellness. To address the challenges of self-management of mental illnesses, we have developed the MON...