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Structural dataset for the PPARγ V290M mutant

Ana C. Puhl, Paul Webb, Igor Polikarpov • Data in Brief (2016)

Loss-of-function mutation V290M in the ligand-binding domain of the peroxisome proliferator activated receptor γ (PPARγ) is associated with a ligand resistance syndrome (PLRS), characterized by partial lipodystrophy and severe insulin resis...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2016.03.082

A Focus on Simulation in Medical Informatics

James G. Anderson • Journal of the American Medical Informatics Association (2002)

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1167 PMC: 346642

The Use and Interpretation of Quasi-Experimental Studies in Medical Informatics

Anthony D. Harris, Jessina C. McGregor, Eli N. Perencevich, Jon P. Furuno et al. • Journal of the American Medical Informatics Association (2005)

Quasi-experimental study designs, often described as nonrandomized, pre-post intervention studies, are common in the medical informatics literature. Yet little has been written about the benefits and limitations of the quasi-experimental ap...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1749 PMC: 1380192

Medical Informatics and the Science of Cognition

V L Patel, David R. Kaufman • Journal of the American Medical Informatics Association (1998)

Recent developments in medical informatics research have afforded possibilities for great advances in health care delivery. These exciting opportunities also present formidable challenges to the implementation and integration of technologie...

OPENALEX Open Access DOI: https://doi.org/10.1136/jamia.1998.0050493 PMC: 61330

Sakha Language in a Northern Industrial Monotown: Linguistic Distribution in Speech Repertoire of Sakha People

I. A. Danilov • Научный диалог (2024)

This study explores the functioning of the Yakut language in the conditions of the northern industrial monotown Mirny (Republic of Sakha (Yakutia)). The study identifies the features of linguistic distribution in the speech repertoire of et...

DOAJ Open Access (DOAJ) DOI: 10.24224/2227-1295-2024-13-5-48-66

Evaluation of the SH-SY5Y cell line as an in vitro model for potency testing of a neuropeptide-expressing AAV vector

Jeanette Zanker, Daniela Hüser, Adrien Savy, Sara Lázaro-Petri et al. • Frontiers in Molecular Neuroscience (2023)

Viral vectors have become important tools for basic research and clinical gene therapy over the past years. However, in vitro testing of vector-derived transgene function can be challenging when specific post-translational modifications are...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2023.1280556

Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of IK(M) or IK(DR) and in the Stimulation of IMEP

Wei-Ting Chang, Wei-Ting Chang, Wei-Ting Chang, Ping-Yen Liu et al. • Frontiers in Pharmacology (2020)

Remdesivir (RDV, GS-5734), a broad-spectrum antiviral drug in the class of nucleotide analogs, has been particularly tailored for treatment of coronavirus infections. However, to which extent RDV is able to modify various types of membrane ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2020.01091

Developments in Exploring Fungal Secondary Metabolites as Antiviral Compounds and Advances in HIV-1 Inhibitor Screening Assays

Bruce Nzimande, John P. Makhwitine, Nompumelelo P. Mkhwanazi, Sizwe I. Ndlovu • Viruses (2023)

The emergence of drug-resistant Human Immunodeficiency Virus-1 strains against anti-HIV therapies in the clinical pipeline, and the persistence of HIV in cellular reservoirs remains a significant concern. Therefore, there is a continuous ne...

DOAJ Open Access (DOAJ) DOI: 10.3390/v15051039

Comparative Phytochemical Analysis of the Aerial Parts of <i>Pelargonium radula</i> and <i>Geranium macrorrhizum</i> Cultivated in Bulgaria Using GC-MS and HPLC

Debora Sabotinova, Petya Boycheva, Nadezhda Ivanova, Velichka Andonova et al. • Pharmaceuticals (2026)

Background: Geraniaceae species are widely used in traditional medicine. Pelargonium radula and Geranium macrorrhizum are aromatic medicinal plants traditionally used in Bulgaria for their antimicrobial, anti-inflammatory, and wound-healing...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph19030346

Bioentrepreneurship in Medical Biotechnology

Neeti Sharma • Advances in business strategy and competitive advantage book series (2021)

Being a developing sector, biotechnology combines both medical science and various facets of a sustainable environment. Scientific innovations from academics and industry contribute towards the rise of bioentrepreneurship across the world. ...

OPENALEX DOI: https://doi.org/10.4018/978-1-7998-7411-9.ch012

Modeling and analysis for dynamical Doppler shifts on terahertz communication signals propagating in inhomogeneous hypersonic plasma sheath

Xiangmeng Lin, Junyi Zhang, Kai Yuan, Ziyang Zhao et al. • AIP Advances (2025)

Previous studies have shown that terahertz (THz) signals could penetrate hypersonic plasma sheaths. Thus, it is considered to be a potential solution to the “blackout” problem. Nevertheless, although previous studies have systematically rev...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0281985

ZAGREB INDICES AND THE THERMAL BEHAVIOR OF STEROIDS: A QUANTITATIVE GRAPH-BASED STUDY

Sarwa Hita, I Gede Adhitya Wisnu Wardhana, Nguyen Dang Hoa Nghiem, Ni Komang Tri Dharmayani • Barekeng (2026)

In mathematical chemistry, graph theory provides a systematic and quantitative framework for understanding the relationship between molecular structure and the physicochemical properties of compounds. This study investigates the correlation...

DOAJ Open Access (DOAJ) DOI: 10.30598/barekengvol20iss4pp2937-2948

The Evolution of Homo Economicus

Natalia V. Komarovskaia • Vestnik MGIMO-Universiteta (2016)

The article provides a review of the ways in which interdisciplinary research in modern economic thought gives a more realistic understanding of human behavior and economic decision making. On the one hand, economic imperialism drove wider ...

DOAJ Open Access (DOAJ)

Sharing competences in strategic alliances: a case study of the Cosan and Shell biofuel venture

Luciana Florêncio de Almeida, Cláudio Antonio Pinheiro Machado Filho • RAUSP: Revista de Administração da Universidade de São Paulo (2013)

In a competitive world, the way a firm establishes its organizational arrangements may determine the enhancement of its core competences and the possibility of reaching new markets. Firms that find their skills to be applicable in just one ...

DOAJ Open Access (DOAJ) DOI: 10.5700/rausp1093

LOCAL COMMUNITY’S ECOLOGICAL KNOWLEDGE IN THE SELECTION OF SHADING TREESFOR TRADITIONAL AGROFORESTRY SYSTEM (NUTMEG “DUSUNG”) IN AMBON

Messalina Lovenia Salampessy, Indra Gumay Febryano, Iskar Bone • Jurnal Penelitian Sosial dan Ekonomi Kehutanan (2017)

Local ecological knowledge is closely linked to decision-making process for planting tree. The aims of this study are to describe and explain local community’s decision-making process in the selection of shading trees on their lands accordi...

DOAJ Open Access (DOAJ) DOI: doi.org/10.20886/jpsek.2017.14.2.135-142

An integrated vehicle routing model to optimize agricultural products distribution in retail chains

W. Madushan Fernando, Amila Thibbotuwawa, H. Niles Perera, Peter Nielsen et al. • Cleaner Logistics and Supply Chain (2024)

The Vehicle Routing Problem (VRP) represents a thoroughly investigated domain within operations research, yielding substantial cost savings in global transportation. The fundamental objective of the VRP is to determine the optimal route pla...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.clscn.2023.100137

The Attitudes of Residents towards Agro-tourism Impacts and Its Effects on Participation in Agro-tourism Development: The Case Study of Vietnam.

Nha Thi Huynh Nguyen, Asst. Prof. Dr. Suvit Suwanno, Assoc. Prof. Dr. Weerapon Thongma, Assoc. Prof. Dr. Parichart Visuthismajarn • African Journal of Hospitality, Tourism and Leisure (2018)

This paper investigates the residents' participation in agro-tourism development by examining their attitudes towards the impacts of agro-tourism on economic, socio-culture, and environment. The data was obtained from a survey of residents ...

DOAJ Open Access (DOAJ)

Digital Marketing Strategies and Guest Booking Behavior in Hospitality: A Narrative Literature Review in the Philippines

Nicole Marion Polines, Nora Mendoza, Jordan Ortaleza, Rey Eliseo Regidor • JPAIR (2026)

The hospitality industry has been reshaped by digital transformation, with hotels and resorts increasingly relying on online platforms to attract and convert guests. This narrative literature review synthesizes studies published between 201...

DOAJ Open Access (DOAJ) DOI: 10.7719/jpair.v65i1.1017