Academic Articles & Research Papers

Microclimate characteristics, temporal dynamics of soil bacterial communities, and potential co-occurrence network differences between greenhouse and open-field cultivation environments.

Stress-dependent ribosome-associated proteomics reveals a role for Sis1 in thermotolerance and virulence in Cryptococcus neoformans.

A nationwide study of pathogens in hospitalized patients with lower respiratory tract infections by metagenomic next-generation sequencing.

From microbiome profiling to clinical translation: designing microbiome studies for clinical actionability.

Prevalence and quantification of viable Campylobacter species in retail chicken: a comparative study using viability digital polymerase chain reaction and conventional culture methods.

Illuminating the microbial 'dark matter' in obesity: integrated multi-omics approaches to characterize uncultured taxa and their potential metabolic crosstalk with host pathways.

Invasive fungal diseases in immunocompetent adults: emerging patterns and clinical challenges.

Environmental Drivers of Nontuberculous Mycobacteria in Tropical Freshwater Systems.

Structural characteristics and regulatory mechanisms of the ocular surface microbiota and their relationship with ocular surface health.

Culturable Leptospira spp. exhibit no detectable spatial or matrix-associated structuring in Estero de Paco, Manila, Philippines.

Mutation-induced penicillin binding protein 2A inactivation through CRISPR-dCas9 gene editing in methicillin-resistant S. aureus.

Genomic insights into replicons and conjugative transfer systems of bla(NDM)-positive plasmids in the Enterobacter cloacae complex.

Identification and Functional Assessment of the First Placental Adhesin of Treponema pallidum That May Play Critical Role in Congenital Syphilis

Syphilis is a global, re-emerging sexually transmitted infection and congenital syphilis remains a major cause of adverse pregnancy outcomes due to bacterial infection in developing nations with a high rate of fetus loss. The molecular mech...

Molecular detection of antibiotic resistance genes in Staphylococcus aureus isolated from poultry farms of Kathmandu Valley, Nepal

Abstract Background Antimicrobial resistance (AMR) has emerged as a critical global health challenge and is currently addressed through a “One Health” approach that investigates its occurrence in humans, animals, and the environment, as wel...

An Investigation of Potential Health Risks from Zoonotic Bacterial Pathogens Associated with Farm Rats

Background: The 21st century has seen a wide range of diseases resulting from zoonotic infections, of which bacterial infections have led to outbreaks of food-borne diseases. Aim: The study looks at bacterial pathogen carriage by farm rats ...

Process-Programmed Extraction–Structure–Activity Relationships (ESAR) in edible and medicinal mushroom polysaccharides: a mechanistic and application-oriented framework

Background: Edible and medicinal mushroom polysaccharides (EMMPs) display wide-ranging bioactivities, yet progress has been limited by siloed workflows. Extraction, structural analysis, and biological evaluation are often conducted independ...

Stage-Dependent Within-Individual Comparison Reveals SIV-Specific Activation/Exhaustion Shift in Rhesus Macaques

It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohor...

Evaluation of resistance modulation in MDR Pseudomonas aeruginosa and Klebsiella pneumoniae using peppermint oil nanoemulsion: integrating antibacterial assays and molecular modeling

IntroductionMultidrug-resistant urinary tract pathogens, primarily Klebsiella pneumoniae and Pseudomonas aeruginosa, represent a significant and growing public health challenge. The overuse of antibiotics has accelerated the development of ...

Casearia tomentosa fruit extracts exposed larvicidal activity and morphological alterations in Culex quinquefasciatus and Aedes albopictus under in vitro and semi field conditions

Abstract Mosquitoes are notorious insects that transmit a wide range of infectious diseases, including zika, malaria, chikungunya, filariasis, and dengue. The overuse and incorrect application of synthetic pesticides to control mosquitoes h...

Multifunctional properties of Phlomis aurea extracts: In-vitro antioxidant, antimicrobial, anticancer, potent repellency against two mosquito vectors and molecular docking studies

Abstract To develop economically viable and environmentally benign methodologies for organic reactions and reveal the practical utility of transitional natural compounds and their derivatives. In addition, a new research method to conduct d...