Academic Articles & Research Papers

Epidemiology and risk factors of dementia

ementia refers to a syndrome that is characterised by progressive deterioration of cognitive functions.Neuropsychiatric symptoms, such as apathy, agitation, and depression, are also common.With increasing loss of function, a patient is grad...

The M235T polymorphism in the angiotensinogen gene is not a major risk factor for diabetic nephropathy; a meta-analysis

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in diabetes patients. The angiotensin AGT M235T gene polymorphism, which is linked to the renin-angiotensin-aldosterone system (RAAS), has been extensive...

Efficacy of integrative medicine using Yinhua-based herbal granules on herpangina: A Bayesian network meta-analysis of randomized controlled trials

Background: Different Traditional Chinese Medicine (TCM) in the format of granules, such as Kanggan Granules (KangGs), Kouyanqing Granules (KouGs), Lianhua Qingwen Granules (LQGs), Qingkailing Granules (QGs) and Xiao'er Qingjie Granules (XQ...

The effect of replacing saturated fat with mostly n-6 polyunsaturated fat on coronary heart disease: a meta-analysis of randomised controlled trials

Abstract Background A cornerstone of conventional dietary advice is the recommendation to replace saturated fatty acids (SFA) with mostly n-6 polyunsaturated fatty acids (PUFA) to reduce the risk of coronary heart disease (CHD). Many clinic...

Clinical outcomes in various coronary artery bypass grafting techniques: A systematic review and network meta-analysis.

Sensitivity and Features of Computed Tomography in Diagnosis of COVID-19 Pneumonia: A Meta-analysis

Introduction: Early diagnosis of COVID-19 is important for disease treatment and management. Computed Tomography (CT) is a fast and easy modality for diagnosis and management plan of patients with COVID-19. In the literature, several stu...

Independent association of general and central adiposity with risk of gallstone disease: observational and genetic analyses

BackgroundGeneral obesity is a well-established risk factor for gallstone disease (GSD), but whether central obesity contributes additional independent risk remains controversial. We aimed to comprehensively clarify the effect of body fat d...

The New Statistics

We need to make substantial changes to how we conduct research. First, in response to heightened concern that our published research literature is incomplete and untrustworthy, we need new requirements to ensure research integrity. These in...

Public Health Communication

Contents: Preface. Introduction. R. Hornik, Public Health Communication: Making Sense of Contradictory Evidence. Part I: Deliberate Trials. J.K. Worden, B.S. Flynn, Using Mass Media to Prevent Cigarette Smoking. P. Palmgreen, L. Donohew, E....

Oxford Textbook of Public Health

SECTION 1: THE DEVELOPMENT OF THE DISCIPLINE OF PUBLIC HEALTH 1.1 The scope and concerns of public health 1.2 The history and development of public health in high-income countries 1.3 The history and development of public health in low- and...

Efficacy of anti-PD-1/PD-L1 plus chemotherapy in treatment-naïve advanced HER2-negative gastric adenocarcinoma among different PD-L1 intervals: an updated meta-analysis and reconstructed individual patient-level data analysis.

Cardiovascular and metabolic outcomes associated with moderate-to-severe atopic dermatitis: A systematic review and meta-analysis

Background: Chronic systemic inflammation in individuals with moderate-to-severe atopic dermatitis (AD) potentially predisposes them to metabolic and cardiovascular diseases. Nevertheless, evidence with regard to such association is limited...

Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.

Meta-analysis of MitraClip and PASCAL for transcatheter mitral edge-to-edge repair

Abstract Background Despite the promising results of both MitraClip and PASCAL systems for the treatment of mitral regurgitation (MR), there is limited data on the comparison of both systems regarding their safety and efficacy. We aim to co...

Causal analysis between altered levels of interleukins and obstructive sleep apnea

BackgroundInflammation proteins including interleukins (ILs) have been reported to be related to obstructive sleep apnea (OSA). The aims of this study were to estimate the levels for several key interleukins in OSA and the causal effects be...

Effects of bystander interventions on school bullying: a systematic review and meta-analysis.

The Effects of N-acetylcysteine on Inflammatory Markers and Homocysteine: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Background: Recently a number of trials investigated the effect of N-acetylcysteine (NAC) administration on inflammatory markers and homocysteine (Hcy). However, their findings are controversial. The aim of this paper is to present a meta-a...

Clinical accuracy and applications of intraoral scanners in periodontal assessment: A systematic review and meta-analysis.

Systematic review and meta-analysis on the efficacy and safety of combining repetitive transcranial magnetic stimulation with sertraline for adolescent depression in China.

Digital and artificial intelligence-assisted medication management for older adults with chronic diseases: a systematic review and meta-analysis of randomized controlled trials.