Reset
Showing 20 of 450 academic articles

Innovative polymer-based electrochemical platform for detecting ESAT-6 in human blood for pulmonary tuberculosis diagnosis

Xiu-An Ye, Shu-Hong Lin, Liang-Yu Chen, Jie-Ren Li et al. • Sensing and Bio-Sensing Research (2025)

Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), necessitates early diagnosis for effective patient care. Despite advancements in TB diagnostics, there remains an urgent need to discover innovative non-sputum-based m...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.sbsr.2025.100816

THE VALUES FOSTERED BY HEALTH TECHNOLOGY

Pascale Lehoux, Bryn Williams–Jones, Myriam Hivon, Geneviève Daudelin et al. • Australasian Medical Journal (2012)

The values and knowledge claims circulating in the health policy arena regarding health technologies (i.e., devices, diagnostics) are complex and often include arguments...

OPENALEX Open Access DOI: https://doi.org/10.21767/amj.2012.1484

Serum amyloid beta 42 levels correlated with metabolic syndrome and its components

Kecheng Li, Kecheng Li, Xiaoli Zhou, Xiaoli Zhou et al. • Frontiers in Endocrinology (2024)

IntroductionBeta-amyloid accumulation in the brain appears to be a key initiating event in Alzheimer’s disease (AD), and factors associated with increased deposition of beta-amyloid are of great interest. Enhanced deposition of amyloid-β pe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fendo.2024.1278477

Advances in High Throughput Proteomics Profiling in Establishing Potential Biomarkers for Gastrointestinal Cancer

Md Zahirul Islam Khan, Shing Yau Tam, Helen Ka Wai Law • Cells (2022)

Gastrointestinal cancers (GICs) remain the most diagnosed cancers and accounted for the highest cancer-related death globally. The prognosis and treatment outcomes of many GICs are poor because most of the cases are diagnosed in advanced me...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells11060973

Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

Kapil Sayal, Laura Wyatt, Louise Thomson, Grace Holt et al. • Health Technology Assessment (2025)

Background Emotional disorders are common in children and young people and can significantly impair their quality of life. Evidence-based treatments require a timely and appropriate diagnosis. The utility of standardised diagnostic assessme...

DOAJ Open Access (DOAJ) DOI: 10.3310/GJKS0519

Anticancer and anti-angiogenic activities of mannooligosaccharides extracted from coconut meal on colorectal carcinoma cells in vitro

Patthra Pason, Chakrit Tachaapaikoon, Waralee Suyama, Rattiya Waeonukul et al. • Toxicology Reports (2024)

Colorectal carcinoma (CRC) is one of the most common malignancies, though there are no effective therapeutic regimens at present. This study aimed to investigate the inhibitory effects of mannooligosaccharides extracted from coconut meal (C...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2023.12.010

Hormonal Influences on ADC Values in Breast Tissues: A Scoping Review of DWI in Pre- and Post-menopausal Women [version 3; peer review: 2 approved]

Neil Barnes Abraham, Abhimanyu Pradhan, Suresh Sukumar, Sneha Ravichandran et al. • F1000Research (2025)

Background Breast cancer remains a significant global health concern, with early diagnosis and risk factor identification crucial for improving outcomes. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) measurements...

DOAJ Open Access (DOAJ) DOI: 10.12688/f1000research.153999.3

Real World Data in Health Technology Assessment of Complex Health Technologies

Milou Milou, Johan Pontén, Rick A. Vreman, Aukje K. Mantel-Teeuwisse et al. • Frontiers in Pharmacology (2022)

The available evidence on relative effectiveness and risks of new health technologies is often limited at the time of health technology assessment (HTA). Additionally, a wide variety in real-world data (RWD) policies exist among HTA organiz...

OPENALEX cc-by DOI: https://doi.org/10.3389/fphar.2022.837302 PMC: 8866967

Use of qualitative and mixed methods research in diagnostic technology evaluation and implementation: insights from a systematic review

Caity Roleston, Umasha Ukwatte, Nia Roberts, Gail N. Hayward et al. • Diagnostic and Prognostic Research (2026)

Abstract Background Development of new diagnostic health technologies is increasing, alongside interest in how they can be implemented into health services. Evaluation of new diagnostic tests has typically consisted of technical and diagnos...

DOAJ Open Access (DOAJ) DOI: 10.1186/s41512-026-00240-z

ASSESSMENT OF THE LEARNING CURVE IN HEALTH TECHNOLOGIES

Craig Robert Ramsay, Adrian Grant, Sheila A. Wallace, Paul H. Garthwaite et al. • International Journal of Technology Assessment in Health Care (2000)

OBJECTIVE: We reviewed and appraised the methods by which the issue of the learning curve has been addressed during health technology assessment in the past. METHOD: We performed a systematic review of papers in clinical databases (BIOSIS, ...

OPENALEX DOI: https://doi.org/10.1017/s0266462300103149

Assessing, Pricing and Funding Point-of-Care Diagnostic Tests for Community-Acquired Acute Respiratory Tract Infections–Overview of Policies Applied in 17 European Countries

Sabine Vogler, Friederike Windisch • Antibiotics (2022)

Point-of-care diagnostic tests for community-acquired acute respiratory tract infections (CA-ARTI) can support doctors by improving antibiotic prescribing. However, little is known about health technology assessment (HTA), pricing and fundi...

DOAJ Open Access (DOAJ) DOI: 10.3390/antibiotics11080987

Oh brother, where art tau? Amyloid, neurodegeneration, and cognitive decline without elevated tau

Lauren E. McCollum, Sandhitsu R. Das, Long Xie, Robin de Flores et al. • NeuroImage: Clinical (2021)

Mild cognitive impairment (MCI) can be an early manifestation of Alzheimer’s disease (AD) pathology, other pathologic entities [e.g., cerebrovascular disease, Lewy body disease, LATE (limbic-predominant age-related TDP-43 encephalopathy)], ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102717

Key Variables for Effective eHealth Designs for Individuals With and Without Mental Health Disorders: 2^12-4 Fractional Factorial Experiment

Rotondi, Armando J, Grady, Jonathan, Hanusa, Barbara H, Haas, Gretchen L et al. • Journal of Medical Internet Research (2021)

BackgroundeHealth applications not only offer the potential to increase service convenience and responsiveness but also expand the ability to tailor services to improve relevance, engagement, and use. To achieve these goals, it is critical ...

DOAJ Open Access (DOAJ) DOI: 10.2196/23137

Assessing Acceptance and Intention to Use of Home Telemonitoring Among Patients with Liver Cirrhosis: Development and Initial Psychometric Validation of a TAM-Based Questionnaire

Ruxandra-Cristina Marin, Horia Păunescu, Călin Muntean, Daniel Vasile Balaban et al. • Diagnostics (2026)

Background/Objectives: Liver cirrhosis (LC) is a major cause of morbidity and mortality requiring continuous monitoring and early recognition of clinical deterioration. Home telemonitoring is increasingly considered a supportive strategy fo...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics16162635

Медицинская информатика [Medical Informatics]

B.A. Kobrinsky, T.V. Zarubina • Zenodo (CERN European Organization for Nuclear Research) (2012)

A 2009 Russian-language textbook by Boris A. Kobrinsky and Tatyana V. Zarubina on medical informatics. The book covers the principles and methods of information technology in medicine, including medical information systems, biomedical data ...

OPENALEX cc-by DOI: https://doi.org/10.5281/zenodo.21930521

A Virtual Reading Center Model Using Crowdsourcing to Grade Photographs for Trachoma: Validation Study

Christopher J Brady, R Chase Cockrell, Lindsay R Aldrich, Meraf A Wolle et al. • Journal of Medical Internet Research (2023)

BackgroundAs trachoma is eliminated, skilled field graders become less adept at correctly identifying active disease (trachomatous inflammation—follicular [TF]). Deciding if trachoma has been eliminated from a district or if treatment strat...

DOAJ Open Access (DOAJ) DOI: 10.2196/41233

Data Mining Techniques in Medical Informatics

U. Rajendra Acharya, Wenwei Yu • The Open Medical Informatics Journal (2010)

The advent of high-performance computing has benefited various disciplines in finding practical solutions to their problems, and our health care is no exception to this.Signal processing, image processing, and data mining tools have been de...

OPENALEX cc-by-nc DOI: https://doi.org/10.2174/1874431101004010021 PMC: 2916206

Automated measurement of CD8+ T-cell distribution at the tumor epithelial–stromal interface is associated with NSCLC immunotherapy benefit and transcriptomic pathways

Patrick Leo, Hauke Kolster, Hartmut Koeppen, Jennifer Giltnane et al. • Journal of Pathology Informatics (2026)

Whereas anti-PD-(L)1 therapies are widely used in cancer treatment, only a subset of patients achieve long-term survival. Companion diagnostics based on PD-L1 expression have limited predictive power for these therapies, motivating developm...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jpi.2026.100688

Real-World Evaluation of AI-Driven Diabetic Retinopathy Screening in Public Health Settings: Validation and Implementation Study

Mona Duggal, Anshul Chauhan, Vishali Gupta, Ankita Kankaria et al. • JMIR Medical Informatics (2025)

Abstract BackgroundArtificial intelligence (AI) algorithms offer an effective solution to alleviate the burden of diabetic retinopathy (DR) screening in public health settings. However, there are challenges in translating diagno...

DOAJ Open Access (DOAJ) DOI: 10.2196/67529