Academic Articles & Research Papers

High prevalence of tau pathologies in late-onset psychosis: A PET study.

Machine Learning Approaches for Clinical Psychology and Psychiatry

Machine learning approaches for clinical psychology and psychiatry explicitly focus on learning statistical functions from multidimensional data sets to make generalizable predictions about individuals. The goal of this review is to provide...

Automated speech-fluency explanations for schizophrenia diagnosis

Abstract Schizophrenia is a chronic and severe mental disorder that still relies on time-intensive, clinician-administered assessments. Although several automated approaches have been proposed to support diagnosis, these systems often lack ...

When more is not always better: exercise dose and children’s cognitive development from an interpretable machine learning perspective

BackgroundExercise intervention has been associated with cognitive development in children. However, current study methods have not clarified the potential nonlinear association between exercise dosage and cognitive ability, and interpretab...

Identification and multidimensional characterization of two distinct autism spectrum disorder subtypes.

Midbrain endocannabinoids actuate dopamine-based action selection

Summary: Quickly adapting behavior to changing environments is key for survival. Brain dopamine signals reinforce actions that procure rewards and avoid adverse outcomes. However, the molecular mechanisms within the circuits that actuate th...

The voice of depression: speech features as biomarkers for major depressive disorder

Abstract Background Psychiatry faces a challenge due to the lack of objective biomarkers, as current assessments are based on subjective evaluations. Automated speech analysis shows promise in detecting symptom severity in depressed patient...

Rethinking schizophrenia: Optimizing care pathways in Europe from the first episode of psychosis to long-term care.

Real-world effectiveness and safety of intranasal esketamine for treatment-resistant depression: Data from the enTRD registry.

PERMEPSY: a multicentre, randomized, double-blind proof-of-concept trial of personalized metacognitive training for adults with psychosis — a study protocol

BackgroundWhile psychological interventions are effective at improving symptoms of psychosis, accessible, cost- and time-efficient treatments remain limited. Personalized medicine has emerged as a promising approach, tailoring interventions...

Structural brain complexity is associated with linguistic complexity in psychosis.

Machine learning reveals a multimodal, transdiagnostic signature of emotion dysregulation vulnerability across patients, offspring, and controls.

Mechanistically Distinct Subtypes of Individuals With Cocaine Use Disorder Identified by Neural Cue Reactivity and Prediction of Clinical Outcomes.

Artificial intelligence and Psychiatry: An overview

Artificial intelligence and increasing misinformation

With the recent advances in artificial intelligence (AI), patients are increasingly exposed to misleading medical information. Generative AI models, including large language models such as ChatGPT, create and modify text, images, audio and ...

Unsupervised machine learning identifies distinct ALS molecular subtypes in post-mortem motor cortex and blood expression data

Abstract Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been utilised for patient stratification in ALS as they can disentangle complex disease lands...

Machine minds: Artificial intelligence in psychiatry

Diagnostic and interventional aspects of psychiatric care can be augmented by the use of digital health technologies. Recent studies have tried to explore the use of artificial intelligence-driven technologies in screening, diagnosing, and ...

Sycophancy and Extended Engagement with Publicly Accessible Generative AI: Aligning Deployment with Mental Health Needs.

Information leakage and performance overestimation in EEG-based schizophrenia detection: evidence from literature and empirical analyses.

AI-assisted neurocognitive assessment protocol for older adults with psychiatric disorders

IntroductionEvaluating neurocognitive functions and diagnosing psychiatric disorders in older adults is challenging due to the complexity of symptoms and individual differences. An innovative approach that combines the accuracy of artificia...