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Effects of Vitex trifolia L. leaf extracts and phytoconstituents on cytokine production in human U937 macrophages

Hai-Ning Wee, Soek-Ying Neo, Deepika Singh, Hui-Chuing Yew et al. • BMC Complementary Medicine and Therapies (2020)

Abstract Background Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in co...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12906-020-02884-w

The Identification of a Novel Spider Toxin Peptide, Lycotoxin-Pa2a, with Antibacterial and Anti-Inflammatory Activities

Min Kyoung Shin, In-Wook Hwang, Bo-Young Jang, Kyung-Bin Bu et al. • Antibiotics (2023)

With the increasing challenge of controlling infectious diseases due to the emergence of antibiotic-resistant strains, the importance of discovering new antimicrobial agents is rapidly increasing. Animal venoms contain a variety of function...

DOAJ Open Access (DOAJ) DOI: 10.3390/antibiotics12121708

Integrated Geotechnical Approach and GIS for Identification of Geological Resources Exploitable Quarries for Sustainable Development in Ifni Inlier and Lakhssas Plateau (Western Anti Atlas, Morocco)

Mohamed Mahmoud Sebbab, Abdelhadi El Ouahidi, Mehdi Ousbih, Seddik Ouboulahcen et al. • Applied Sciences (2023)

The purpose of this paper is to identify, quantify and delineate the areas with suitable aggregate resources in the Precambrian massif of Ifni and the limestone plateau of Lakhssas (southwest Morocco). To fulfill this objective, a study was...

DOAJ Open Access (DOAJ) DOI: 10.3390/app13063932

Modelling effective diffusion for accurate NMR pore size analysis in nano- and microporous rocks

Michał Fajt, Grzegorz Machowski, Bartosz Puzio, Artur T. Krzyżak • Scientific Reports (2025)

Abstract Low-field NMR (LF-NMR) is a widely applied technique for evaluating pore size distribution (PSD) in porous materials. Conventional approaches typically assume surface-controlled spin-spin relaxation and negligible diffusion contrib...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-20379-x

Inhibition of Citrus Huanglongbing Disease by <i>Paenibacillus polymyx</i> KN-03 and Analysis with Transcriptome and Microflora

Yuehua Yang, Fangkui Wang, Jialin Jiang, Ling Jiang • Agronomy (2023)

Soil drench treatment using Paenibacillus polymyxa strain KN-03 was applied to citrus plants infected with Candidatus Liberibacter asiaticus (CLas). The infection status was assessed using PCR and a real-time quantitative PCR detection syst...

DOAJ Open Access (DOAJ) DOI: 10.3390/agronomy13122958

Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

Integrated Farming System (IFS): A Review

Shweta Khobragade, Sanghamitra Mohapatra, M. Mahananda, Aarti Singh et al. • International Journal of Economic Plants (2021)

Adoption of Integrated Farming System (IFS) leads to sustainability and stability in farm income through multiple enterprises that aim at maximum utilization of available natural resources to meet the family needs. It aims at generating a t...

DOAJ Open Access (DOAJ)

Protocol to measure human IL-6 secretion from CAR T cell-primed macrophage and monocyte lineage cells in vitro and in vivo using humanized mice

Thao Nguyen, Toshiaki Yoshikawa, Yusuke Ito, Hitomi Kasuya et al. • STAR Protocols (2024)

Summary: Chimeric antigen receptor (CAR) T cell therapy often causes serious toxicities, such as cytokine release syndrome (CRS), mainly due to interleukin-6 (IL-6) secreted by monocyte lineage cells. Here, we describe a protocol to generat...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.xpro.2024.103423

A review on the recent mechanisms investigation of PFAS electrochemical oxidation degradation: mechanisms, DFT calculation, and pathways

Gengyang Li, Mason Peng, Qingguo Huang, Ching-Hua Huang et al. • Frontiers in Environmental Engineering (2025)

Per- and polyfluoroalkyl substances (PFAS) have drawn public concern recently due to their toxic properties and persistence in the environment, making it urgent to eliminate PFAS from contaminated water. Electrochemical oxidation (EO) has s...

DOAJ Open Access (DOAJ) DOI: 10.3389/fenve.2025.1568542

Microplastic as a vector of heavy metals and chemicals in aquatic ecosystems

Javid Imanpour Namin, Fereshteh Hajiaghaei Ghaazi Mahalleh • Caspian Journal of Environmental Sciences (2025)

Microplastics (MPs) have become a symbol of modern life and their fate in the environment is an issue of great concern. MPs have attracted attention for their widespread distribution, especially in the aquatic ecosystems. MPs can act as a v...

DOAJ Open Access (DOAJ) DOI: 10.22124/cjes.2024.8016

Operating pesticide use reduction within the boundary of food security in peri-urban settings

Yuquan W. Zhang, Bruce A. McCarl, Zhengwei Cao, Qiang Li et al. • Fundamental Research (2022)

Pesticide use in peri-urban areas affects the urban environment and public health, and reducing the use may present food security issues for urban dwellers. In this study, we explore how a municipality-adopted goal of a 20% reduction in pes...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.fmre.2022.04.003

Fine mapping of QYrsv.swust-1BL for resistance to stripe rust in durum wheat Svevo

Xinli Zhou, Guoyun Jia, Yuqi Luo, Xin Li et al. • Frontiers in Plant Science (2024)

Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a serious disease that affects wheat worldwide. There is a great need to develop cultivars with combinations of all-stage resistance (ASR) and adult-plant resistance (APR)...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpls.2024.1395223

Astaxanthin biofortification enhances tobacco tolerance to lead stress through boosting antioxidant defense, reducing Pb accumulation, and modulating detoxification pathways

Zhongyang Du, Mengjing Liang, Xiaodan Wang, Yizhen Liu et al. • Journal of Advanced Research (2026)

Introduction: Heavy metal pollution including lead (Pb) has become one of the serious global issues threatening food security, human health, and the ecosystem. Exogenous application of astaxanthin (ATX), a potent natural antioxidant, has be...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jare.2025.07.038

The Impact of Bio-Based Fertilizer Integration Into Conventional Grassland Fertilization Programmes on Soil Bacterial, Fungal, and Nematode Communities

Demi Ryan, Anna Karpinska, Patrick J. Forrestal, S. M. Ashekuzzaman et al. • Frontiers in Sustainable Food Systems (2022)

Phosphorus (P) is an essential plant macro-nutrient applied to soil in agriculture, mainly sourced from non-renewable mined phosphate-rock, of which readily accessible reserves are currently under pressure, while global food demand continue...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2022.832841