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Showing 20 of 9,045 academic articles

Non-therapist identification of falling hazards in older adult homes using digital photography

Katherine C. Ritchey, Deborah Meyer, Gillian H. Ice • Preventive Medicine Reports (2015)

Evaluation and removal of home hazards is an invaluable method for preventing in-home falls and preserving independent living. Current processes for conducting home hazard assessments are impractical from a whole population standpoint given...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pmedr.2015.09.004

Health researchers' experience collaborating with patient partners: a qualitative study

Magaly Brodeur, Catherine Wilhelmy, Denis Boutin, Amélie Deschamps et al. • Research Involvement and Engagement (2025)

Abstract Background Patient-oriented research (POR) and patient engagement (PE) have been increasingly adopted over recent decades, as they generate many positive academic and patient outcomes within various health research fields. While th...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40900-025-00730-2

Risks and Benefits of Clinical Diagnosis Around the Time of Dementia Onset

Melinda C. Power ScD, Victoria Willens MPH, Christina Prather MD, Ali Moghtaderi PhD et al. • Gerontology and Geriatric Medicine (2023)

Diagnostic delay in dementia is common in the U.S. Drivers of diagnostic delay are poorly understood, but appear related to misconceptions about dementia, stigma, concerns about autonomy, the nature of the diagnostic process, and provider-r...

DOAJ Open Access (DOAJ) DOI: 10.1177/23337214231213185

Cohort profile: the Taiwan Initiative for Geriatric Epidemiological Research - a prospective cohort study on cognition

Pei-Iun Hsieh, Te-Hsuan Huang, Jeng-Min Chiou, Jen-Hau Chen et al. • Epidemiology and Health (2024)

The Taiwan Initiative for Geriatric Epidemiological Research (TIGER) was founded in 2011 to elucidate the interrelationships among various predictors of global and domain-specific cognitive impairment, with the aim of identifying older adul...

DOAJ Open Access (DOAJ) DOI: 10.4178/epih.e2024057

Sex- and age-specific effects of fat distribution on bone mineral density

Xiao Lin, Jun-Jie Yang, Bei Huang, Peng-Xin Wang et al. • Experimental Gerontology (2026)

Background: BMI cannot distinguish fat distribution and may mask the true effects of different fat depots on bone mineral density (BMD). To investigate sex- and age-specific associations between fat distribution and BMD and its mediating ro...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2026.113301

Copper exposure association with prevalence of non-alcoholic fatty liver disease and insulin resistance among US adults (NHANES 2011–2014)

Chen Chen, Qi Zhou, Ruiyue Yang, Zhu Wu et al. • Ecotoxicology and Environmental Safety (2021)

Background: Excessive copper (Cu) has risky effect on insulin resistance (IR), oxidative stress and inflammation. Instead, some studies reported serum Cu to be protective for non-alcoholic fatty liver disease (NAFLD). The aim of this study ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ecoenv.2021.112295

Factors Associated with Quality of Life Among Older Adults with Chronic Disease in Taiwan

Hsiao-Mei Chen, Ching-Min Chen • International Journal of Gerontology (2017)

Background: There have been many studies reviewing quality of life (QoL) of older population and found an inverse association between QoL and chronic diseases. However, previous studies have focused only on that of people with specific dise...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ijge.2016.07.002

A nationwide study on immunosenescence biomarkers profile in older adults: ELSI-Brazil

Maria Luiza Lima-Silva, Karen Cecília Lima Torres, Juliana Vaz de Melo Mambrini, Nathalia Coimbra Brot et al. • Experimental Gerontology (2024)

Immunosenescence is a phenomenon caused by changes in the immune system, and part of these changes involves an increase in circulating immunological biomarkers, a process known as “Inflammaging.” Inflammaging can be associated with many dis...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2024.112433

Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology (2026)

Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2026.113057

Discharge preparation experiences of intergenerational caregivers for premature infants in China’s NICU: a qualitative study

Yan Zhang, Ling Jiang, Jinyu Zhu, Sijia Shen et al. • BMJ Paediatrics Open (2026)

Background Proper discharge preparation by family caregivers is essential for improving the growth and development of preterm infants and lowering their readmission rates. Within China’s unique family cultural context, intergenerational car...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjpo-2026-004695 PMC: PMC13691880

Equipment in Senior Gyms: Influence on the Behavior of Blood Pressure and Heart Rate of Elderlies

Sillas Oliveira Leonel Júnior, Mateus Dias Antunes, Ramon Gustavo de Moraes Ovando, Ana Paula Serra de Araújo et al. • Geriatrics, Gerontology and Aging (2024)

OBJECTIVE: To analyze the behavior of blood pressure and heart rate in elderly people practicing physical exercises in Maringá, Paraná, Brazil. METHODS: 70 elderly volunteers were evaluated, 41 women and 29 men, with a mean age of 67.2 ± 6....

DOAJ Open Access (DOAJ) DOI: 10.5327/Z2447-211520171700042

Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers

Meng Zhang, Ping He, Zhigang Bian • Frontiers in Molecular Neuroscience (2021)

Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2021.685143

Rare genetic diseases associated with G-quadruplex-induced replication stress

Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology (2026)

Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-026-09966-4

Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu et al. • Experimental Gerontology (2024)

The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cel...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2024.112633

Effectiveness of music-based interventions in acute care settings for people living with dementia to reduce anxiety and enhance the care experience: A systematic review.

Victoria McArthur, Susan Everington, Martyn Patel • Archives of Gerontology and Geriatrics Plus (2024)

Introduction: Dementia is a global health priority, with an increasing percentage of overall hospital bed days occupied by people with dementia (PWD). This combined with increased demand and availability of complex scanning means that there...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2024.100087

Linking Spiritual and Religious Coping With the Quality of Life of Community-Dwelling Older Adults and Nursing Home Residents

Luciano Magalhães Vitorino BSN, MSc, Gail Low RN, BSN, MA, PhD, Lucila Amaral Carneiro Vianna PhD • Gerontology and Geriatric Medicine (2016)

Objective: This study examined the effect of Positive and Negative Spiritual and Religious Coping (SRC) upon older Brazilian’s quality of life (QOL). Method: A secondary analysis of data collected from 77 nursing home residents (NHRs; M age...

DOAJ Open Access (DOAJ) DOI: 10.1177/2333721416658140

Impact of age-friendly living environment and intrinsic capacity on functional ability in older adults: a cross-sectional study

Yi-Shan Jiang, Hong Shi, Yu-Ting Kang, Ji Shen et al. • BMC Geriatrics (2023)

Abstract Background The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-04089-5

Protocol for the Tallaght University Hospital Institute for Memory and Cognition-Biobank for Research in Ageing and Neurodegeneration

Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open (2023)

Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2023-077772