Academic Articles & Research Papers

Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study

Abstract Revascularization procedures, including percutaneous coronary intervention (PCI), for coronary artery disease (CAD) are increasingly performed in Korea. However, studies on blood pressure control targets in these patients remain in...

Evaluating key predictors of breast cancer through survival: a comparison of AFT frailty models with LASSO, ridge, and elastic net regularization

Abstract Background Frailty models are extensively utilized in survival analysis to address unobserved heterogeneity among individuals. However, selecting the most robust model for survival prediction, especially in the context of high-dime...

Comparative Optimisation of Managed Portfolios Across Market Regimes

The study contributes a contemporary perspective to the evolving discourse on the relative performance of three managed investing styles: Deep Value, Growth, and Blended portfolios. Deep Value investing focuses on fundamentally strong but u...

Ethical and social implications of approaching death prediction in humans - when the biology of ageing meets existential issues

Abstract Background The discovery of biomarkers of ageing has led to the development of predictors of impending natural death and has paved the way for personalised estimation of the risk of death in the general population. This study inten...

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

On Combined Maximal Precedence–Exceedance Test with Application to HIV Clinical Trials

This paper proposes a combined maximal precedence–exceedance test (MPErs) that integrates maximal precedence and maximal exceedance statistics tests to provide sensitivity to both early and late distributional differences between two sample...

Determination of Novel Estimations for the Slater Difference and Applications

The field of mathematical inequalities has exerted a profound influence across a multitude of scientific disciplines, making it a captivating and expansive domain ripe for research investigation. This article offers estimations for the Slat...

Discussion of “optimal reinsurance designs based on risk measures: a review” by Jun Cai and Yichun Chi

Beyond airborne spread: a dual-route Wells-Riley extension for estimating norovirus infection risk in Ghanaian pediatric wards

Background: The classic Wells–Riley model (CWRM) is a well-established framework for estimating airborne infection risk in shared indoor environments. This study extends the framework to simultaneously incorporate fecal–oral transmission, a...

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...

Modeling antiretroviral therapy adherence among people living with HIV: a cross-sectional study at Pantang Hospital, Ghana

Abstract Background Poor adherence to antiretroviral therapy (ART) continues to undermine HIV treatment outcomes in sub-Saharan Africa, including Ghana. Objective This study aimed to quantify ART treatment adherence among people living with...

Mathematical Modeling of Leptospirosis With Misdiagnosis

Leptospirosis is a widespread zoonotic bacterial disease that continues to pose a major public health challenge, particularly in developing countries where it causes substantial morbidity, mortality, and economic losses. A key problem in co...

Improved representation of laminar and turbulent sheet flow in subglacial drainage models

Subglacial hydrology models struggle to reproduce seasonal drainage patterns that are consistent with observed subglacial water pressures and surface velocities. We modify the standard sheet-flow parameterization within a coupled sheet–chan...

Entropy Measures for Plithogenic Sets and Applications in Multi-Attribute Decision Making

Plithogenic set is an extension of the crisp set, fuzzy set, intuitionistic fuzzy set, and neutrosophic sets, whose elements are characterized by one or more attributes, and each attribute can assume many values. Each attribute has a corres...

Cost of inaction: a framework to estimate the economic cost of missing a patient with tuberculosis in the Indian context

Objectives To estimate the economic impact of failure to find and treat tuberculosis disease and prevent tuberculosis infection from progressing to active disease.Design Estimating the economic cost of not finding and treating a patient suf...

Factor de Descuento, Flujos Futuros y Deterioro de Activos Tangibles e Intangibles

Este trabajo, es un análisis exploratorio-descriptivo-cuantitativo; simulación matemática de un flujo creciente y decreciente de ingresos futuros a tasas bajas y altas de interés; para deducir sus resultados. Objetivos: Evaluar un facto...

Which scoring systems are useful for predicting the prognosis of lower gastrointestinal bleeding? Old and new

Abstract Background The incidence of lower gastrointestinal bleeding is on the rise, prompting the creation of various scoring systems to forecast patient’s outcomes. But there is no single unified scoring system and these scoring systems c...

Estimated pulse wave velocity and progression to advanced cardiovascular–kidney–metabolic syndrome: a population-based longitudinal study with supportive external cross-sectional evidence

BackgroundCardiovascular–kidney–metabolic (CKM) syndrome captures the interconnected burden of metabolic risk factors, chronic kidney disease, and cardiovascular disease. Evidence remains limited regarding simple and clinically accessible m...

An Overview of Earthworm Biodiversity in Afghanistan with New Records for the Country (Clitellata: Megadrili)

In this paper a batch of earthworms from Afghanistan was studied and previous reports on the earthworm fauna of the country were evaluated. In the present study, earthworms were collected by digging and hand sorting, and fixed in 80% ethano...

祁连山白唇鹿的分布

白唇鹿（Cerous albirostris）为我国特产珍贵动物,栖于高寒高原地区,系青藏高原的特有种。自1876年6月,Cossack Kalmynin在甘肃省西部祁连山采集第一只白唇鹿以来,有关祁连山白唇鹿分布散见于各区系研究（中国科学院青海甘肃综合考察队,1964;王香亭等,1982等）中,...