Academic Articles & Research Papers

Machine learning for precision medicine

Precision medicine is an emerging approach to clinical research and patient care that focuses on understanding and treating disease by integrating multi-modal or multi-omics data from an individual to make patient-tailored decisions. With t...

Comparing Clinical Metadata Fusion Strategies for Diabetic and Hypertensive Retinopathy Classification

Structured clinical variables may complement fundus photographs, but the most appropriate point at which to integrate them into a retinal foundation model remains uncertain. This study compares an image-only baseline with three strategies f...

Discovering subtypes with imaging signatures in the Motoric Cognitive Risk Syndrome Consortium using weakly supervised clustering

ABSTRACT INTRODUCTION Understanding the heterogeneity of brain structure in individuals with the Motoric Cognitive Risk Syndrome (MCR) may improve the current risk assessments of dementia. METHODS We used data from six cohorts from the MCR ...

State-level disparities and socio-demographic determinants of intention to use contraception among non-using women in South-West Nigeria.

Taxonomy-based data representation for data mining: an example of the magnitude of risk associated with H. pylori infection

Abstract Background The amount of available and potentially significant data describing study subjects is ever growing with the introduction and integration of different registries and data banks. The single specific attribute of these data...

Identification of arachidonic acid metabolism-related diagnostic markers in heart failure based on bioinformatics analysis and machine learning

BackgroundHeart failure (HF) represents the terminal phase of multiple cardiovascular conditions and is associated with significant morbidity and mortality rates. Arachidonic acid (AA), an essential fatty acid, plays a crucial role in modul...

Machine learning-based diagnostic prediction of minimal change disease: model development study

Abstract Minimal change disease (MCD) is a common cause of nephrotic syndrome. Due to its rapid progression, early detection is essential; however, definitive diagnosis requires invasive kidney biopsy. This study aims to develop non-invasiv...

Resistance to Medical Artificial Intelligence

Abstract Artificial intelligence (AI) is revolutionizing healthcare, but little is known about consumer receptivity to AI in medicine. Consumers are reluctant to utilize healthcare provided by AI in real and hypothetical choices, separate a...

Glycolytic reprogramming in cancer: tumour cell metabolism, immune modulation, and therapeutic opportunities.

Artificial intelligence model to predict pregnancy and multiple pregnancy risk following in vitro fertilization-embryo transfer (IVF-ET)

Objective: To decrease multiple pregnancy risk and sustain optimal pregnancy chance by choosing suitable number of embryos during transfer, this study aims to construct artificial intelligence models to predict the pregnancy outcome and mul...

PERMEPSY: a multicentre, randomized, double-blind proof-of-concept trial of personalized metacognitive training for adults with psychosis — a study protocol

BackgroundWhile psychological interventions are effective at improving symptoms of psychosis, accessible, cost- and time-efficient treatments remain limited. Personalized medicine has emerged as a promising approach, tailoring interventions...

The Impacts of Robotics, Artificial Intelligence On Business and Economics

In the Industrial Age that humanity has entered long time ago with steam series has caused to primitive mechanization in production. With the development of internet and mobile technologies, electronics, nano technology, advances in medicin...

Artificial intelligence: Implications for the future of work

Artificial intelligence (AI) is a broad transdisciplinary field with roots in logic, statistics, cognitive psychology, decision theory, neuroscience, linguistics, cybernetics, and computer engineering. The modern field of AI began at a smal...

KGRD: a knowledge-graph-augmented automated reasoning framework for diagnosis and counselling of paediatric rare genetic disorders.

PANDA pediatric arousal neural detection architecture.

Tackling visual impairment: emerging avenues in ophthalmology

Visual impairment, stemming from genetic, degenerative, and traumatic causes, affects millions globally. Recent advancements in ophthalmology present novel strategies for managing and potentially reversing these conditions. Here, we explore...

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

ABSTRACT Saikosaponin b1 (Ssb1), a natural oleanane‐type triterpenoid saponin, exhibits antifibrosis activity by inhibiting the activation of hepatic stellate cells (HSCs), but the specific underlying molecular mechanisms are unknown. Here,...

Artificial intelligence in cardiology

Introducing Artificial Intelligence Training in Medical Education

Health care is evolving and with it the need to reform medical education. As the practice of medicine enters the age of artificial intelligence (AI), the use of data to improve clinical decision making will grow, pushing the need for skillf...

Single lead electrocardiographic detection of left ventricular systolic dysfunction in pediatric and congenital heart disease.