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Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study

Ji-Yeon Park, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho et al. • Endocrinology and Metabolism (2022)

Background Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the association of cumul...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2022.1416

Cost of inaction: a framework to estimate the economic cost of missing a patient with tuberculosis in the Indian context

Salmaan Keshavjee, Meredith B Brooks, Tom Nicholson, Viswanath Pingali • BMJ Open (2023)

Objectives To estimate the economic impact of failure to find and treat tuberculosis disease and prevent tuberculosis infection from progressing to active disease.Design Estimating the economic cost of not finding and treating a patient suf...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-070717

Estimated pulse wave velocity and progression to advanced cardiovascular–kidney–metabolic syndrome: a population-based longitudinal study with supportive external cross-sectional evidence

Wenjiao Zhang, Wenjiao Zhang, Wenbo Yang, Wenbo Yang et al. • Frontiers in Cardiovascular Medicine (2026)

BackgroundCardiovascular–kidney–metabolic (CKM) syndrome captures the interconnected burden of metabolic risk factors, chronic kidney disease, and cardiovascular disease. Evidence remains limited regarding simple and clinically accessible m...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2026.1875961

Urban Flood Zoning Using an Integrated Hydrological-Hydraulic Watershed Modeling Approach, Case Study: Districts 21 and 22 of Tehran

Ali Nasiri, Esmaeil Salimi, Morteza Delfan Azari, Jafar Yazdi et al. • دانش پیشگیری و مدیریت بحران (2025)

Flood zoning has extensive applications in flood management and is considered one of the fundamental and critical pieces of information in flood risk management. Flood zoning in urban areas is much more challenging than modeling in floodpla...

DOAJ Open Access (DOAJ)

Seasonal variation of pesticides and associated risks in Guangdong's drinking water sources

Zhineng Liu, Xiaolan Lao, Dongjing Zhou, Jianwei Liang et al. • Desalination and Water Treatment (2025)

Pesticides are essential for crop protection and agricultural yield enhancement. However, their entry into water bodies, particularly drinking water sources, poses threats to human health and aquatic ecosystems. The seasonal variation, and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dwt.2025.101208

Air pollution mapping and variability over five European cities

Karine Sartelet, Jules Kerckhoffs, Eleni Athanasopoulou, Lya Lugon et al. • Environment International (2025)

Mapping urban pollution is essential for assessing population exposure and addressing associated health impacts. High urban concentrations are due to the proximity of sources such as traffic or residential heating, and to urban density with...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.envint.2025.109474

Thoracic electrical impedance tomography identifies heterogeneity in lungs associated with respiratory disease in cattle. A pilot study

Olivia Brabant, Yuliya V. Karpievitch, Yuliya V. Karpievitch, Alphons Gwatimba et al. • Frontiers in Veterinary Science (2024)

Respiratory disease in cattle is a significant global concern, yet current diagnostic methods are limited, and there is a lack of crush-side tests for detecting active disease. To address this gap, we propose utilizing electrical impedance ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2023.1275013

Assessment of the knowledge, attitudes and practices level on toxoplasmosis and its seroprevalence in selected high-risk groups in Cebu, Philippines

Adrian P. Ybañez, Adrian P. Ybañez, Grahambell B. Sabanate, Serafin L. Garciano et al. • Frontiers in Veterinary Science (2026)

Toxoplasmosis, a zoonotic disease caused by Toxoplasma gondii, poses significant health risks, especially to high-risk individuals who are exposed to cats. This study aimed to assess the knowledge, attitudes, and practices (KAP) related to ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2026.1758610

Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from <i>Dirofilaria immitis</i> in an In Vitro Endothelial Model

Manuel Collado-Cuadrado, Claudia Alarcón-Torrecillas, Alfonso Balmori-de la Puente, Iván Rodríguez-Escolar et al. • Animals (2024)

Heartworm disease, caused by Dirofilaria immitis, is a vector-borne zoonotic disease, (mainly affecting canids and felids) causing chronic vascular and pulmonary pathology in its early stages, which worsens with parasite load and/or death o...

DOAJ Open Access (DOAJ) DOI: 10.3390/ani14233371

Understanding the Attitudes of Communities to the Social, Economic, and Cultural Importance of Working Donkeys in Rural, Peri-urban, and Urban Areas of Ethiopia

Martha Geiger, Jo Hockenhull, Henry Buller, Gebre Tefera Engida et al. • Frontiers in Veterinary Science (2020)

Working donkeys (Equus africanus asinus) are vital to the development and support of people's livelihoods in rural, peri-urban, and urban areas of Ethiopia. However, despite their critical role in providing transport, food security, and inc...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2020.00060

Melatonin Regulates Lipid Metabolism in Porcine Cumulus–Oocyte Complexes via the Melatonin Receptor 2

Jun-Xue Jin, Jing-Tao Sun, Chao-Qian Jiang, Hong-Di Cui et al. • Antioxidants (2022)

Previous studies suggest that the inclusion of melatonin (MTn) in in vitro maturation protocols improves the developmental competence of oocytes by scavenging reactive oxygen species (ROS). However, the molecular mechanisms integrating mela...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11040687

The Effects of Deoxynivalenol on the Ultrastructure of the <i>Sacculus Rotundus</i> and <i>Vermiform Appendix</i>, as Well as the Intestinal Microbiota of Weaned Rabbits

Chunyang Wang, Libo Huang, Pengwei Wang, Quancheng Liu et al. • Toxins (2020)

Deoxynivalenol (DON) is a mycotoxin found in grains that poses a potential threat to human and animal health, and the gastrointestinal tract is the primary target organ. There are few studies focused on the toxicology of DON to rabbits, esp...

DOAJ Open Access (DOAJ) DOI: 10.3390/toxins12090569

Bioecological Study on the Sand Flies (Diptera: Psychodidae, Phlebotominae) in Sari County, North of Iran

Nasibeh Hosseini-Vasoukolaei, Leila Ghavibazou, Amir Ahmad Akhavan, Ahmad Ali Enayati et al. • Journal of Arthropod-Borne Diseases (2023)

Background: Phlebotomine sand flies are vectors of Leishmania species, the causative agents of leishmaniasis in the world. Present study aimed to evaluate the bioecological aspects of sand flies in different ecotopes in Sari County, north o...

DOAJ Open Access (DOAJ) DOI: 10.18502/jad.v16i2.11806

Motivation and context of concurrent stimulant and opioid use among persons who use drugs in the rural United States: a multi-site qualitative inquiry

R. J. Fredericksen, R. Baker, A. Sibley, A. T. Estadt et al. • Harm Reduction Journal (2024)

Abstract Background In recent years, stimulant use has increased among persons who use opioids in the rural U.S., leading to high rates of overdose and death. We sought to understand motivations and contexts for stimulant use among persons ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12954-024-00986-z

Morphological identification and genetic characterization of Anopheles stephensi in Somaliland

Said Ali, Jeanne N. Samake, Joseph Spear, Tamar E. Carter • Parasites & Vectors (2022)

Abstract Malaria control in Somaliland depends on the effective identification of potential malaria vectors, particularly those that may be invasive. The malaria vector Anopheles stephensi has been detected in multiple countries in the Horn...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13071-022-05339-y

Implementation of the therapeutic use of hydroxyurea for sickle cell disease management in resource-constrained settings: a systematic review of adoption, cost and acceptability

Joyce Gyamfi, Temitope Ojo, Dorice Vieira, Nessa Ryan et al. • BMJ Open (2020)

Objectives Mortality associated with sickle cell disease (SCD) is high in many low- and middle-income countries (LMICs). Hydroxyurea, a medicine to effectively manage SCD, is not widely available in resource-constrained settings. We identif...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2020-038685

Traffic Fatalities and Urban Infrastructure: A Spatial Variability Study Using Geographically Weighted Poisson Regression Applied in Cali (Colombia)

Harvy Vivas Pacheco, Diego Rodríguez-Mariaca, Ciro Jaramillo, Andrés Fandiño-Losada et al. • Safety (2023)

The mobility plan and the road infrastructure works implemented, together with the Bus Rapid Transit (BRT) connected bus system in its first two phases, generated optimistic expectations about the reduction of lethal crashes in the city. Th...

DOAJ Open Access (DOAJ) DOI: 10.3390/safety9020034

Point of Care Ultrasonographic Life Support in Emergency (PULSE)—a quasi-experimental study

Noman Ali, Abdul Ahad Chhotani, Sannia Perwaiz Iqbal, Salman Muhammad Soomar et al. • International Journal of Emergency Medicine (2023)

Abstract Background Many physicians use point-of-care ultrasound (PoCUS) in their clinical practice to improve their diagnostic capabilities, accuracy, and timeliness. Over the last two decades, the use of PoCUS in the emergency room has dr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12245-023-00525-w

Critical review of leachate pathways, groundwater contamination, and health risks in tropical urban aquifers

M. Bamini, R. K. Somashekar • Discover Environment (2026)

Abstract Rapid, under-serviced urbanization across the tropical belt has left many cities dependent on open dumps. These dumps and poorly engineered landfills often sit above shallow, heavily used aquifers. This review uses the Doddabidarak...

DOAJ Open Access (DOAJ) DOI: 10.1007/s44274-026-01021-7

Intersecting inequalities in experiences of violence among Brazilian adults: a multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) of the 2019 National Health Survey

Wilson H. Hammett, James Macinko • International Journal for Equity in Health (2026)

Abstract Introduction Existing quantitative studies of violence victimization in Brazil often examine individual demographic and socioeconomic risk factors, limiting insight into how identities can intersect to co-produce vulnerability or r...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12939-026-02818-x