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Comparative analysis of chemical toxicological studies of pregabalin in neuropathic pain management (review)

Nargiz Parkhatkyzy, Alma Shukirbekova, Zumrad Usmanalieva, Kundyzay Mirzakir et al. • Journal of Pharmacy & Pharmacognosy Research (2026)

Context: The use of pregabalin in neuropathic pain management has been increasingly associated with concerns regarding toxicity, particularly in cases of overdose, misuse, and co-exposure with central nervous system depressants. In parallel...

DOAJ Open Access (DOAJ) DOI: 10.56499/jppres_14.3.2550

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Anca Otilia Farcas, Mihai Ciprian Stoica, Septimiu Voidazan, Carmen Corina Radu et al. • Diagnostics (2026)

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics16152432

Forensic Application of Next Generation Sequencing Technology in the Typing of Y Chromosome Genetic Marker

YANG Yue , TAO Rui-yang , LI Min , et al. • Fayixue Zazhi (2021)

The paternal inheritance characteristics of Y chromosome have been widely used in the forensic genetics field to detect the genetic markers in the non-recombining block, and used in the studies such as, genetic relationship identification, ...

DOAJ Open Access (DOAJ) DOI: 10.12116/j.issn.1004-5619.2020.501205

Improving Minutiae Image of Latent Fingerprint Detection on Non-Porous Surface Materials under UV Light Using Sulfur Doped Carbon Quantum Dots from Magnolia Grandiflora Flower

David Nugroho, Won-Chun Oh, Saksit Chanthai, Rachadaporn Benchawattananon • Nanomaterials (2022)

In this study, carbon quantum dots (CQDs) from Magnolia Grandiflora flower as a carbon precursor were obtained using a hydrothermal method under the optimized conditions affected by various heating times (14, 16, 18, and 20 min) and various...

DOAJ Open Access (DOAJ) DOI: 10.3390/nano12193277

Does wet-cupping therapy improve repeated sprint ability, perceived wellness, and rating of perceived exertion in young active males?

Ismail Dergaa, Amine Ghram, Mohamed Romdhani, Amine Souissi et al. • Sports Medicine and Health Science (2024)

Wet-cupping therapy (WCT) is one of the oldest known medical techniques, used as a traditional and complementary therapy with a wide application all around the world for general health. Research on the effects of WCT on sports performance a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.smhs.2023.09.007

Genome-based development of 15 microsatellite markers in fluorescent multiplexes for parentage testing in captive tigers

Xiao Zhao, Qiguan Qiu, Chang Li, Dongke Fu et al. • PeerJ (2020)

As one of the most endangered species, tiger (Panthera tigris) inbreeding has become an urgent issue to address. Using a microsatellite (short tandem repeat, STR) identification system, paternity testing may be helpful to avoid inbreeding i...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.8939

Human rights and humanitarian forensic action: the experience in Uruguay

Hugo Rodríguez Almada, Frances Borches Duhalde, Victoria Iglesias Salaverría • Forensic Sciences Research (2022)

Humanitarian Forensic Action (HFA) is considered a new field of Forensic Medicine and Forensic Sciences where the forensic science is applied to different humanitarian activities. In Uruguay, the HFA has been developed based on internationa...

DOAJ Open Access (DOAJ) DOI: 10.1080/20961790.2022.2052591

Bacterial Succession in Microbial Biofilm as a Potential Indicator for Postmortem Submersion Interval Estimation

Finkelbergs Dmitrijs, Juanjuan Guo, Juanjuan Guo, Juanjuan Guo et al. • Frontiers in Microbiology (2022)

Bacteria acts as the main decomposer during the process of biodegradation by microbial communities in the ecosystem. Numerous studies have revealed the bacterial succession patterns during carcass decomposition in the terrestrial setting. T...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2022.951707

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

Atefeh Varmazyari, Ali Taghizadehghalehjoughi, Cigdem Sevim, Ozlem Baris et al. • Toxicology Reports (2020)

Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2020.04.011

Detection Techniques for Synthetic Cannabinoids in Body Fluids and Tissues: A Systematic Review

Sachil Kumar, Tulsidas R. Baggi • Journal of Forensic Science and Medicine (2026)

Synthetic cannabinoids (SCs), originally developed for research purposes in the 1960s, have emerged as a significant concern in clinical and forensic toxicology due to their widespread abuse and unpredictable toxicological effects. These co...

DOAJ Open Access (DOAJ) DOI: 10.4103/jfsm.jfsm_128_25

Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review

Michelangelo Mercogliano, Gloria Spatari, Chiara Noviello, Francesca Di Serafino et al. • International Journal for Equity in Health (2025)

Abstract Introduction Humanitarian crises exacerbate the vulnerability of already fragile healthcare systems and significantly increase the risk of infectious disease outbreaks in low- and middle-income countries (LMICs). This systematic re...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12939-025-02382-w

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

Zhengzhong Luo, Zhenlong Du, Yixin Huang, Tao Zhou et al. • mSystems (2024)

ABSTRACTMetabolic maladaptation in dairy cows after calving can lead to long-term elevation of ketones, such as β-hydroxybutyrate (BHB), representing the condition known as hyperketonemia, which greatly influences the health and production ...

DOAJ Open Access (DOAJ) DOI: 10.1128/msystems.00023-24

Hospitalisations for physical abuse in infants and children less than 5 years, 2013‒2021: a multinational cohort study using administrative data from five European countries

Catherine Quantin, Jonathan Cottenet, Colleen Chambers, Natasha Kennedy et al. • International Journal of Population Data Science (2025)

Objectives Child physical abuse (CPA) is a global public health problem associated with lifelong negative consequences, yet reliable epidemiologic data are lacking. We did a multinational cohort study to analyse trends in CPA hospitalisatio...

DOAJ Open Access (DOAJ) DOI: 10.23889/ijpds.v10i3.3028

Herb-drug interactions of silybinin and cilofexor in beagle dogs based on pharmacokinetics by UPLC-MS/MS

Xinyi Wei, Yanding Su, Qian Cheng, Songmao Liang et al. • Frontiers in Pharmacology (2024)

Objective: A remarkably sensitive, accurate, and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach was developed as a facile and expeditious method for measuring cilofexor concentration in beag...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2024.1334402

The Effect of Yinchenhao Decoction on the Pharmacokinetic Profile of Futibatinib by HPLC-MS/MS

Chunfu Wang, Songmao Liang, Jiachen Xu, Yingfan Zhai et al. • Separations (2024)

Futibatinib is an excellent fibroblast growth factor receptor 1–4 (FGFR 1–4) inhibitor that exhibits selective anti-tumor activeness against FGFR-deregulated tumors. A new high-performance liquid chromatography-tandem mass spectrometry (HPL...

DOAJ Open Access (DOAJ) DOI: 10.3390/separations11070213

Effect of Theaflavins-Soy Protein Isolate Complex Coating on the Quality of Lentinus edodes

Yu WANG, Peiyue ZHAO, Shicheng LEI, Yiyan YANG et al. • Shipin gongye ke-ji (2023)

In order to clarify the preservation effect of theaflavins-soy protein isolate complex coating on Lentinus edodes, a TFs-SPI complex coating agent was prepared by mixing theaflavins and soy protein isolate as subjects, and its structure was...

DOAJ Open Access (DOAJ) DOI: 10.13386/j.issn1002-0306.2022070074

Chemical Diversity of Fuzhuan Brick Teas from Hunan and Shaanxi

ZHANG Ning, YU Shilan, YAN Haoyi, ZHANG Yunjun, HAN Xiaoyu, REN Hongyu, CHEN Yuqing, LING Tiejun, AN Maoqiang • Shipin Kexue (2024)

This study aimed to explore the diversity of metabolites and compare the metabolite profiles of Fuzhuan brick teas from Hunan and Shaanxi, to find out the difference in chemical components between fresh tea leaves and Fuzhuan brick tea and ...

DOAJ Open Access (DOAJ) DOI: 10.7506/spkx1002-6630-20231108-066

Camel Milk Targeting Insulin Receptor—Toward Understanding the Antidiabetic Effects of Camel Milk

Irfa Anwar, Farheen Badrealam Khan, Sajid Maqsood, Mohammed Akli Ayoub et al. • Frontiers in Nutrition (2022)

Camel milk (CM) is known for its beneficial virtues in the human diet and health. This includes its antidiabetic properties demonstrated in many in vitro and in vivo studies. Nevertheless, the scientific rationale behind the molecular and c...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2021.819278