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AY-WB Phytoplasma Secretes a Protein That Targets Plant Cell Nuclei

Xiaodong Bai, Valdir R. Correa, Tania Y. Toruño, El-Desouky Ammar et al. • Molecular Plant-Microbe Interactions (2009)

The fully sequenced genome of aster yellows phytoplasma strain witches' broom (AY-WB; Candidatus Phytoplasma asteris) was mined for the presence of genes encoding secreted proteins based on the presence of N-terminal signal peptides (SP). W...

DOAJ Open Access (DOAJ) DOI: 10.1094/MPMI-22-1-0018

Modeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents

Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology (2022)

Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-022-03753-7

Clinical evaluation of DIAGNOVIR SARS-CoV-2 ultra-rapid antigen test performance compared to PCR-based testing

Ali Aytac Seymen, Ezgi Gulten, Erol Ozgur, Bülend Ortaç et al. • Scientific Reports (2023)

Abstract Coronavirus Disease-19 (COVID-19) is a highly contagious infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The development of rapid antigen tests has contributed to easing the burden on ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-31177-8

Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19

Irandi Putra Pratomo, Dimas R. Noor, Kusmardi Kusmardi, Andriansjah Rukmana et al. • International Journal of Inflammation (2021)

Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a ...

DOAJ Open Access (DOAJ) DOI: 10.1155/2021/1653392

Effects of Luteolin on Human Breast Cancer Using Gene Expression Array: Inferring Novel Genes

Shih-Ho Wang, Chin-Hu Wu, Chin-Chuan Tsai, Tai-Yu Chen et al. • Current Issues in Molecular Biology (2022)

Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the treatment of cancer; however, the downstream regulatory genes and signaling pathways mediating its effects on breast cancer remain unclear. The present s...

DOAJ Open Access (DOAJ) DOI: 10.3390/cimb44050142

Investigating the performance of the fluorescent sensor g-C3N4/Fe/Cu in detecting the Tenofovir drug

Nafiseh Hajian Afarani, Fatemeh Keshavarzi, Kahin Shahanipour, Seyed Amir Zarei • Scientific Reports (2025)

Abstract Tenofovir is an antiviral drug that prevents the replication of AIDS and hepatitis B viruses. To minimize the harmful side effects of the drug on the body, it is essential to determine its precise concentration in the blood. Fluore...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-08877-4

Beyond airborne spread: a dual-route Wells-Riley extension for estimating norovirus infection risk in Ghanaian pediatric wards

Jennifer Belt Antwi, Nana Kena Frempong • Mathematics in Medical and Life Sciences (2026)

Background: The classic Wells–Riley model (CWRM) is a well-established framework for estimating airborne infection risk in shared indoor environments. This study extends the framework to simultaneously incorporate fecal–oral transmission, a...

DOAJ Open Access (DOAJ) DOI: 10.1080/29937574.2026.2714847

Isolation, characterization and virulence assessment of Type 1d CP bovine viral diarrhea virus originating from Inner Mongolia, China

Luyao Hao, Luyao Hao, Fengmiao Zhao, Fengmiao Zhao et al. • Frontiers in Veterinary Science (2025)

In recent years, bovine viral diarrhea virus (BVDV) has been associated with increased respiratory and gastrointestinal diseases in cattle. Comprehensive monitoring and investigations into the virus's pathological features are crucial for d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2025.1554986

Identification and genomic characterization of a novel porcine parvovirus in China

Yajing Guo, Guangzhi Yan, Shengnan Chen, Hui Han et al. • Frontiers in Veterinary Science (2022)

Porcine parvoviruses (PPVs) are a group of small non-enveloped viruses with seven species (porcine parvovirus 1–7, PPV1-7) have been identified. In this study, a novel porcine parvovirus, provisionally named porcine parvovirus 8 (PPV8), was...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2022.1009103

Coronary artery bypass grafting outcomes of patients with human immunodeficiency virus: a population-based study of National Inpatient Sample from 2015 to 2020

Renxi Li, Deyanira J. Prastein, Brian G. Choi • Scientific Reports (2024)

Abstract Individuals affected by human immunodeficiency virus (HIV) have a growing demand for coronary artery bypass grafting (CABG) due to heightened risk for cardiovascular diseases and extended life expectancy. However, CABG outcomes in ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-65518-y

HCV-associated mixed cryoglobulinemia and b-cell non-Hodgkin's lymphoma - pathogenetically related problems

S Yu Milovanova, L V Lysenko (Kozlovskaya), L Yu Milovanova, N N Mrykhin et al. • Терапевтический архив (2018)

Hepatitis C virus (HCV) is a global population problem due to its high prevalence, usually late diagnosis, the difficulties of treatment. In the prognosis of patients with HCV not only hepatic, but increasingly frequent of extrahepatic HCV ...

DOAJ Open Access (DOAJ) DOI: 10.26442/terarkh2018906112-120

Immunological and Viral Profiles of Squamous Cell Carcinoma in Transplant and Non‐Transplant Patients in Singapore

Choon Chiat Oh, Boon Yee Lim, Elizabeth Chun Yong Lee, Bavani Kannan et al. • JEADV Clinical Practice (2025)

ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) remains poorly understood at the molecular level, both in the immunocompetent and immunosuppressed population with skin of colour. Data on the diversity of viruses found in cSCC i...

DOAJ Open Access (DOAJ) DOI: 10.1002/jvc2.70142

CCR4, a RNA decay factor, is hijacked by a plant cytorhabdovirus phosphoprotein to facilitate virus replication

Zhen-Jia Zhang, Qiang Gao, Xiao-Dong Fang, Zhi-Hang Ding et al. • eLife (2020)

Carbon catabolite repression 4 (CCR4) is a conserved mRNA deadenylase regulating posttranscriptional gene expression. However, regulation of CCR4 in virus infections is less understood. Here, we characterized a pro-viral role of CCR4 in rep...

DOAJ Open Access (DOAJ) DOI: 10.7554/eLife.53753

Assessing the Knowledge, Attitudes, and Vaccination Practices Towards COVID-19 Vaccination Among Mainland Chinese Nursing Students and Interns: A Multicenter Cross-Sectional Study

Qin Z, Ye X, Liu H, Tao Y et al. • Infection and Drug Resistance (2023)

Zhuzhu Qin,1,* Xinxin Ye,2,* Huanju Liu,3 Yining Tao,4 Xutong Zheng,1 Yanxia Zhong,5 Danfeng Chen,1 Wan Ye,6 Chenju Zhan7 1School of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China; 2Department of S...

DOAJ Open Access (DOAJ)

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis (2024)

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rpth.2024.102615

Chitosan nanoparticles as next-generation carriers for veterinary DNA vaccines: Mechanisms, immune responses, and translational prospects

Miguel González-Lozano, José Alberto Cano-Buendía • Veterinary World (2025)

Background and Aim: Chitosan-based DNA nanoparticles have emerged as a promising next-generation platform for veterinary vaccines, addressing several limitations of conventional attenuated, inactivated, and recombinant formulations. Chitosa...

DOAJ Open Access (DOAJ) DOI: 10.14202/vetworld.2025.3826-3838

Adaptation of SIVmac to baboon primary cells results in complete absence of in vivo baboon infectivity

Veronica Obregon-Perko, Amanda Mannino, Jason T. Ladner, Vida Hodara et al. • Frontiers in Cellular and Infection Microbiology (2024)

While simian immunodeficiency virus (SIV) infection is non-pathogenic in naturally infected African nonhuman primate hosts, experimental or accidental infection in rhesus macaques often leads to AIDS. Baboons, widely distributed throughout ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2024.1408245

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Supachai Sakkhachornphop, Sudarat Hadpech, Tanchanok Wisitponchai, Chansunee Panto et al. • Viruses (2018)

Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, AnkGAG1D4, showed a negative effect on the viral assembly of the HIV...

DOAJ Open Access (DOAJ) DOI: 10.3390/v10110625