Academic Articles & Research Papers

Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

Identification of the correct targets is a key element for successful drug development. However, there are limited approaches for predicting drug targets for specific diseases using omics data, and few have leveraged expression profiles fro...

Machine learning and applications in microbiology

To understand the intricacies of microorganisms at the molecular level requires making sense of copious volumes of data such that it may now be humanly impossible to detect insightful data patterns without an artificial intelligence applica...

Integrated Bioinformatics Analysis and Experimental Verification of Immune Cell Infiltration and the Related Core Genes in Ulcerative Colitis

Danya Zhao,1 Danping Qin,2 Liming Yin,3 Qiang Yang4 1The First School of Clinical Medicine of Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Gastroenterology, The First Affiliated Hospital of Zheji...

Artificial intelligence in cancer target identification and drug discovery

Artificial intelligence is an advanced method to identify novel anticancer targets and discover novel drugs from biology networks because the networks can effectively preserve and quantify the interaction between components of cell systems ...

The role of artificial intelligence in achieving the Sustainable Development Goals

The emergence of artificial intelligence (AI) and its progressively wider impact on many sectors requires an assessment of its effect on the achievement of the Sustainable Development Goals. Using a consensus-based expert elicitation proces...

Advances in ligand-targeted nanodelivery systems for leukemia therapy: from single- to dual-ligand strategies

Abstract Background Leukemia is a highly heterogeneous and aggressive hematological malignancy. Current therapeutic approaches (e.g. chemotherapy, radiotherapy, small-molecule targeted therapies, and hematopoietic stem cell transplantation,...

SSMSFuse: A Spectral and Spatial Multiscale Coupling Fusion Model for Hyperspectral and Multispectral Image

Hyperspectral image (HSI) has more spectral information than conventional images, which helps to distinguish targets in a complex scene more accurately. However, HSI typically has a low spatial resolution, which limits their application sce...

Golgi dysfunction in Alzheimer disease: from human multiomic signatures to therapeutic targets.

التحديات التي تثيرها الأسلحة ذاتية التشغيل كأحد تقنيات الذكاء الاصطناعي

صاحب التطور في تكنولوجيا الذكاء الاصطناعي تطوراً مماثلاً في أساليب ووسائل القتال, فظهرت أسلحة جديدة قادرة في ذاتها على تحديد أهدافها والاشتباك معها دون حاجة إلى تدخل بشري, ولذلك أطلق عليها "نظم الأسلحة ذاتية التشغيل" Autonomous Weapons Syst...

Deep nested U-structure network with frequency attention for building semantic segmentation

Abstract The automated segmentation of buildings from remotely sensed imagery has undergone extensive research and application across various industrial domains. Despite this, several challenges persist, including incomplete internal extrac...

Enhancing underwater target detection: Fusion of spatio‐temporal incompletely‐aligned AIS and sonar information via DTW and multi‐head attention mechanism

Abstract In the field of underwater target detection, the passive sonar is an important means of long‐distance target detection. The sonar detection information typically includes both surface and underwater targets, whereas it is a great c...

Artificial intelligence in retina

Major advances in diagnostic technologies are offering unprecedented insight into the condition of the retina and beyond ocular disease. Digital images providing millions of morphological datasets can fast and non-invasively be analyzed in ...