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Cost-Effectiveness Analysis of Pan-Genotypic Sofosbuvir-Based Regimens for Treatment of Chronic Hepatitis C Genotype 1 Infection in China

Hui Jun Zhou, Jing Cao, Hui Shi, Nasheen Naidoo et al. • Frontiers in Public Health (2021)

Background: Hepatitis C virus (HCV) genotype 1 is the most prevalent HCV infection in China. Sofosbuvir-based direct antiviral agent (DAA) regimens are the current mainstays of treatment. Sofosbuvir/velpatasvir (SOF/VEL) and sofosbuvir/ledi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2021.779215

Reported Challenges in Health Technology Assessment of Complex Health Technologies

Milou A. Hogervorst, Rick A. Vreman, Aukje Kaija Mantel-Teeuwisse, Wim Goettsch • Value in Health (2021)

OBJECTIVES: With complex health technologies entering the market, methods for health technology assessment (HTA) may require changes. This study aimed to identify challenges in HTA of complex health technologies. METHODS: A survey was sent ...

OPENALEX cc-by DOI: https://doi.org/10.1016/j.jval.2021.11.1356

An Integrated Approach for Designing and Analyzing Lumbar Vertebral Biomodels with Artificial Disc Replacement

Mhd Ayham Darwich, Katreen Ebrahem, Maysaa Shash, Hasan Mhd Nazha et al. • Applied Mechanics (2023)

This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving exist...

DOAJ Open Access (DOAJ) DOI: 10.3390/applmech4040063

Structural relationships within medical informatics

Theodore Allan Morris, Katherine Wootton McCain (2001)

Medical informatics is the application of information science and information technology to the theoretical and practical problems of biomedical research, clinical practice, and medical education. Although it is broadly interdisciplinary, i...

OPENALEX public-domain DOI: https://doi.org/10.17918/00009917 PMC: 2243843

A Focus on Simulation in Medical Informatics

James G. Anderson • Journal of the American Medical Informatics Association (2002)

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1167 PMC: 346642

Data on biosynthesis of BPAF glucuronide, enzyme kinetics of BPAF glucuronidation, and molecular modeling

Darja Gramec Skledar, Jurij Trontelj, Johanna Troberg, Tihomir Tomašič et al. • Data in Brief (2019)

Bisphenol AF (BPAF) is in the body mainly metabolized to the corresponding bisphenol AF glucuronide (BPAF-G). While BPAF-G is not commercially available, enzyme-assisted synthesis of BPAF-G using the human recombinant enzyme UGT2A1, purific...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2018.12.033

Fusing content and social relationships: a multi-modal heterogeneous graph transformer approach for social bot detection

Jianhong Luo, Chaoqi Jin • EPJ Data Science (2025)

Abstract Social bots pose a significant threat to online platforms, demanding robust methods to detect their increasingly complex behaviors. This paper introduces MM-HGT-Bot, a multi-modal framework that advances the field by operationalizi...

DOAJ Open Access (DOAJ) DOI: 10.1140/epjds/s13688-025-00583-5

Adaptive frequency band attention-guided CNN–BiLSTM for Spatial–Spectral–Temporal EEG emotion recognition

Rabita Hasan, Sheikh Md. Rabiul Islam • Brain Informatics (2026)

Abstract Electroencephalography (EEG)-based emotion recognition has gained increasing attention in affective computing because EEG provides high temporal resolution and reflects intrinsic neural activity. However, reliable emotion recogniti...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40708-026-00319-9

Progress with Formalization in Medical Informatics?

A. A. F. van der Maas, A. J. ten Hoopen, Arthur H. M. ter Hofstede • Journal of the American Medical Informatics Association (2001)

The prevailing view of medical informatics as a primarily subservient discipline in health care is challenged. Developments in both general informatics and medical informatics are described to identify desirable properties of modeling langu...

OPENALEX Open Access DOI: https://doi.org/10.1136/jamia.2001.0080126 PMC: 134552

Bioinformatics and Medical Informatics: Collaborations on the Road to Genomic Medicine?

Víctor Maojo, Casimir A. Kulikowski • Journal of the American Medical Informatics Association (2003)

In this report, the authors compare and contrast medical informatics (MI) and bioinformatics (BI) and provide a viewpoint on their complementarities and potential for collaboration in various subfields. The authors compare MI and BI along s...

OPENALEX Open Access DOI: https://doi.org/10.1197/jamia.m1305 PMC: 264428

Exploring the determinants of patients’ continuance intentions in online health communities from the network effects perspective

Aihui Ye, Runtong Zhang, Hongmei Zhao • Health Informatics Journal (2024)

Objectives: Online health communities (OHCs) facilitate patient-physician interaction and the adoption of online health services. However, few studies explored the impact of network effects on patients’ continuance intentions in OHCs. This ...

DOAJ Open Access (DOAJ) DOI: 10.1177/14604582241300422

Medical informatics

Chamidu Atupelage, Ruwan D. Ranaweera, Mohan Jayathilake, Roshan Yapa et al. • International Conference on Advances in ICT for Emerging Regions (2013)

During last few decades, medical experts have collaborate with the engineers to develop advanced techniques and tools for improving the significances of medical diagnosing techniques. Especially, with the development of high-resolution imag...

OPENALEX DOI: https://doi.org/10.1109/icter.2013.6761203

Understanding Public Perceptions of Lung Cancer in China: Infodemiology Study of Baidu Index and Weibo Posts

Zongyuan Li, Jian Zhang, Yiming Fan, Nan Chen et al. • Journal of Medical Internet Research (2026)

Abstract BackgroundIn China, lung cancer remains a major public health concern and accounts for a substantial proportion of cancer-related deaths nationwide. However, limited research has examined public perceptions of lung canc...

DOAJ Open Access (DOAJ) DOI: 10.2196/85058

Medical Informatics and the Science of Cognition

V L Patel, David R. Kaufman • Journal of the American Medical Informatics Association (1998)

Recent developments in medical informatics research have afforded possibilities for great advances in health care delivery. These exciting opportunities also present formidable challenges to the implementation and integration of technologie...

OPENALEX Open Access DOI: https://doi.org/10.1136/jamia.1998.0050493 PMC: 61330