Academic Articles & Research Papers

Prevalence of fear of hypoglycemia in adults with type 1 diabetes using a newly developed screener and clinician’s perspective on its implementation

Introduction Fear of hypoglycemia (FoH) affects quality of life, emotional well-being, and diabetes management among people with type 1 diabetes (PwT1D). American Diabetes Association’s (ADA) guidelines recommend assessing FoH in clinical p...

Cost effectiveness of vildagliptin versus glimepiride as add-on treatment to metformin for the treatment of diabetes mellitus type 2 patients in Greece

Abstract Objectives This study was designed to assess the cost-effectiveness of vildagliptin versus glimepiride as add-on to metformin in the management of type 2 diabetes mellitus (T2DM) patients in the Greek healthcare setting. Methods A ...

Adherence and health care costs

Aurel O Iuga,1,2 Maura J McGuire3,4 1Johns Hopkins Bloomberg School of Public Health, 2Johns Hopkins University, 3Johns Hopkins Community Physicians, 4Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Medication non...

Advances in microneedle-based drug delivery system for metabolic diseases: structural considerations, design strategies, and future perspectives

Abstract As the prevalence of metabolic diseases such as diabetes and obesity continue to rise, the search for more effective and convenient treatments has become a crucial issue in medical research. Microneedles (MNs), as an innovative dru...

3 Dimenions for Long Term Conditions - creating a sustainable bio-psycho-social approach to healthcare

Introduction: 30% of people with long-term conditions also have a mental health condition. 3Dimensions for Long-term Conditions (3DLC) integrates psychosocial care into heart failure, COPD and resistant hypertension treatment. It is a joint...

The AST/ALT ratio as a mediator of heavy metal exposure and diabetic kidney disease (DKD) risk: A NHANES study

Abstract The potential impact of heavy metal exposure on the progression of diabetic kidney disease (DKD) remains a subject of scientific inquiry. While some studies have hinted at a correlation, definitive evidence is still lacking. It is ...

Missing Values in PIMA Diabetes Dataset and Not Considering It in an Article Accepted in that Journal

The article is a letter to the editor, so it has no abstract....

Antioxidant, Wound Healing Potential and In Silico Assessment of Naringin, Eicosane and Octacosane

1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common complications of poorly managed diabetes mellitus. The most typical reasons are insufficient glycemic management, latent neuropathy, peripheral vascular disea...

Lifestyle interventions to maternal weight loss after birth: a systematic review

Abstract Background Over the past decades, there has been an increase in overweight and obesity in women of childbearing age, as well as the general population. Overweight and obesity are related to a later, increased risk of type 2 diabete...

Epidemiology and Clinical Manifestations of Mucormycosis

Mucormycosis is an emerging angioinvasive infection caused by the ubiquitous filamentous fungi of the Mucorales order of the class of Zygomycetes. Mucormycosis has emerged as the third most common invasive mycosis in order of importance aft...

The M235T polymorphism in the angiotensinogen gene is not a major risk factor for diabetic nephropathy; a meta-analysis

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in diabetes patients. The angiotensin AGT M235T gene polymorphism, which is linked to the renin-angiotensin-aldosterone system (RAAS), has been extensive...

The epidemiology of Helicobacter pylori resistance in a university affiliated hospital: a comparison between two time periods—a cross-sectional design

Abstract Purpose During the last few decades, the increased use of various types of antibiotics in the general population caused a significant change in regional Helicobacter pylori (H. pylori) antibiotic resistance. Our aim is to study the...

Gout epidemiology and comorbidities

OBJECTIVE: To review the epidemiology of gout and associated comorbidities. METHODS: We review the key published studies of the epidemiology of gout and associated comorbidities. RESULTS: The prevalence of gout ranged 1-4% worldwide and inc...

Epidemiology of peripheral neuropathy.

Peripheral neuropathy occurs as a component of several common and many rare diseases.It is heterogenous in aetiology, diverse in pathology, and varied in severity.The term peripheral neuropathy includes symmetric polyneuropathy, single and ...

Gender Differences in the Association Between Serum Uric Acid and Arteriosclerotic Cardiovascular Risk Among Chinese Type 2 Diabetes Mellitus Patients

Hua Yang,1,* Jian Gao,2,* Shuyu Li,1 Huiling Xia,1 Zhangyan Chen,1 Shanzhu Zhu,1 Zhigang Pan1 1Department of General Practice, Zhongshan Hospital of Fudan University, Shanghai, 200030, People’s Republic of China; 2Department of Nutrit...

Epidemiology of Peripheral Artery Disease

New data on the epidemiology of peripheral artery disease (PAD) are available, and they should be integrated with previous data. We provide an updated, integrated overview of the epidemiology of PAD, a focused literature review was conducte...

Fundus imaging based quantum computing: Grading of severity of vision threatening diabetic retinopathy

Diabetic Retinopathy (DR) is a major complication of diabetes that can result in irreversible vision loss if not detected early. Manual ophthalmologic screening is time-consuming and subject to subjectivity, underscoring the need for accura...

Cybersecurity in Artificial Pancreas Experiments

Medical devices have transformed modern health care, and ongoing experimental medical technology trials (such as the artificial pancreas) have the potential to significantly improve the treatment of several chronic conditions, including dia...

Cybersecurity for Connected Diabetes Devices

Diabetes devices are increasingly connected wirelessly to each other and to data-displaying reader devices. Threats to the accurate flow of information and commands may compromise the function of these devices and put their users at risk of...

Dysfunction and therapeutic potential of brown adipose tissue and batokines in obesity and type 2 diabetes mellitus.