Academic Articles & Research Papers

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

Abstract In recent years, long non-coding RNA (lncRNA) research has identified essential roles of these transcripts in virtually all physiological cellular processes including tumorigenesis, but their functions and molecular mechanisms are ...

Artificial neural networks in medical diagnosis

An extensive amount of information is currently available to clinical specialists, ranging from details of clinical symptoms to various types of biochemical data and outputs of imaging devices. Each type of data provides information that mu...

Applications of deep learning in dentistry

Evaluating artificial intelligence for a focal nodular hyperplasia diagnosis using magnetic resonance imaging: preliminary findings

PURPOSE: This study aimed to evaluate the effectiveness of artificial intelligence (AI) in diagnosing focal nodular hyperplasia (FNH) of the liver using magnetic resonance imaging (MRI) and compare its performance with that of radiologists....

Feasibility and effectiveness of automatic deep learning network and radiomics models for differentiating tumor stroma ratio in pancreatic ductal adenocarcinoma

Abstract Objective This study aims to compare the feasibility and effectiveness of automatic deep learning network and radiomics models in differentiating low tumor stroma ratio (TSR) from high TSR in pancreatic ductal adenocarcinoma (PDAC)...

The Application of Deep Learning in Cancer Prognosis Prediction

Deep learning has been applied to many areas in health care, including imaging diagnosis, digital pathology, prediction of hospital admission, drug design, classification of cancer and stromal cells, doctor assistance, etc. Cancer prognosis...

Prediction of lymph node metastasis in papillary thyroid carcinoma using non-contrast CT-based radiomics and deep learning with thyroid lobe segmentation: A dual-center study

Objectives: This study aimed to develop a predictive model for lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) patients by deep learning radiomic (DLRad) and clinical features. Methods: This study included 271 thyroid lobes...

Integrative multiomics-histopathology analysis for breast cancer classification

Abstract Histopathologic evaluation of biopsy slides is a critical step in diagnosing and subtyping breast cancers. However, the connections between histology and multi-omics status have never been systematically explored or interpreted. We...

Deep learning-enabled medical computer vision

A decade of unprecedented progress in artificial intelligence (AI) has demonstrated the potential for many fields-including medicine-to benefit from the insights that AI techniques can extract from data. Here we survey recent progress in th...

Deep learning in cancer diagnosis, prognosis and treatment selection

Deep learning is a subdiscipline of artificial intelligence that uses a machine learning technique called artificial neural networks to extract patterns and make predictions from large data sets. The increasing adoption of deep learning acr...

A review on deep learning in medical image analysis

Ongoing improvements in AI, particularly concerning deep learning techniques, are assisting to identify, classify, and quantify patterns in clinical images. Deep learning is the quickest developing field in artificial intelligence and is ef...

Deep learning in histopathology: the path to the clinic

Comparing deep learning and pathologist quantification of cell-level PD-L1 expression in non-small cell lung cancer whole-slide images

Abstract Programmed death-ligand 1 (PD-L1) expression is currently used in the clinic to assess eligibility for immune-checkpoint inhibitors via the tumor proportion score (TPS), but its efficacy is limited by high interobserver variability...

A 16-year retrospective investigation of granulomatous liver injury in immunocompetent and immunocompromised patients at a tertiary care center.

UAV-Embedded Sensors and Deep Learning for Pathology Identification in Building Façades: A Review

The use of geotechnologies in the field of diagnostic engineering has become ever more present in the identification of pathological manifestations in buildings. The implementation of Unmanned Aerial Vehicles (UAVs) and embedded sensors has...

Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease

Abstract Background Astrocytes and microglia react to Aβ plaques, neurofibrillary tangles, and neurodegeneration in the Alzheimer’s disease (AD) brain. Single-nuclei and single-cell RNA-seq have revealed multiple states or subpopulations of...

Using machine learning to predict persecutory beliefs based on aetiological models of delusions identified in a systematic literature search

Abstract Aetiological models of delusions propose a broad range of predictors. The extent to which these predictors explain variance in persecutory beliefs across the continuum requires systematic investigation. As part of a previous review...

Application of MRI-Based Radiomics in Preoperative Prediction of NF2 Alteration in Intracranial Meningiomas

PurposeThis study aimed to investigate the feasibility of predicting NF2 mutation status based on the MR radiomic analysis in patients with intracranial meningioma.MethodsThis retrospective study included 105 patients with meningiomas, incl...

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

Abstract Background Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen involvement in disease ontogeny and evolution. Primary and 3D stru...

Hyperspectral imaging for the detection of plant pathogens in seeds: recent developments and challenges

Food security, a critical concern amid global population growth, faces challenges in sustainable agricultural production due to significant yield losses caused by plant diseases, with a multitude of them caused by seedborne plant pathogen. ...