Academic Articles & Research Papers

The Immunomodulatory and Anti-Inflammatory Effect of Curcumin on Immune Cell Populations, Cytokines, and In Vivo Models of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a widespread chronic autoimmune disorder affecting the joints, causing irreversible cartilage, synovium, and bone degradation. During the course of the disease, many immune and joint cells are activated, causing...

Clinical genetics of spondylocostal dysostosis: A mini review

Spondylocostal dysostosis is a genetic defect associated with severe rib and vertebrae malformations. In recent years, extensive clinical and molecular diagnosis advancements enabled us to identify disease-causing variants in different gene...

Storage Properties of Double-Layer Films Enriched with <i>Phytolacca americana</i> L. Extract as Active Packaging for African Catfish, with a New Approach to Antioxidant Film Assay and Additional Analysis of <i>P. americana</i> Extract Toxicity on Human Cell Lines

Novel double-layer films based on furcellaran (FUR) and gelatin (GEL) with the addition of Phytolacca americana L. (PA) extract were used as active packaging for African catfish fillets. Films with PA extract have been shown to minimize the...

A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer

Lynch syndrome (LS) is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes. These mutations result in frameshift alterations, leading to the accumulation of errors within microsatellites. Individua...

Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress

Saba Naqvi1, Mohammad Samim2, MZ Abdin3, Farhan Jalees Ahmed4, AN Maitra5, CK Prashant6, Amit K Dinda61Faculty of Engineering and Interdisciplinary Sciences, 2Department of Chemistry, 3Department of Biotechnology, Faculty of Science, 4Depar...

Molecular pathogenesis: Connections between viral hepatitis-induced and non-alcoholic steatohepatitis-induced hepatocellular carcinoma

Hepatocellular carcinoma(HCC) is the sixth most common cancer in the world and is usually caused by viral hepatitis (HBV and HCV), alcoholic, and non-alcoholic fatty liver disease(NAFLD). Viral hepatitis accounts for 80% of HCC cases worldw...

Advances in microneedle-based drug delivery system for metabolic diseases: structural considerations, design strategies, and future perspectives

Abstract As the prevalence of metabolic diseases such as diabetes and obesity continue to rise, the search for more effective and convenient treatments has become a crucial issue in medical research. Microneedles (MNs), as an innovative dru...

Soil Geochemical Properties Influencing the Diversity of Bacteria and Archaea in Soils of the Kitezh Lake Area, Antarctica

It is believed that polar regions are influenced by global warming more significantly, and because polar regions are less affected by human activities, they have certain reference values for future predictions. This study aimed to investiga...

Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties

Structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are potential drug targets due to their role in the virus life cycle. The envelope (E) protein is one of the structural proteins; plays a critical role in v...

In vitro inhibition of SARS-CoV-2 Infection by dry algae powders

Abstract Chlorella spp., Spirulina spp., and fucoidan dry powders, are commercialized as food supplements and are considered safe for human consumption. Their broad-spectrum antiviral properties have been studied, however, their effect agai...

Molecular Characterization of Cryptosporidium Species in Children with Diarrhea in North West of Iran

Cryptosporidium is one of the most common causes of childhood diarrhea in developing countries. The aim of this randomized pilot study was to detect and characterize infective species and determine the genotypes of Cryptosporidium parasites...

Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study

Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a case-control study to assess the alterations of endothelium-dependent flow-mediated...

Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold

Abstract Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature. We prepared bi- o...

The Push for the Free Transfer of IP Rights in Medical Biotechnology

Abstract Biotechnology is a broad range of technologies that employ living organisms or parts of them to make diverse products. Biotechnology, within the American bioeconomy, is a growing topic of concern with recent investments to help add...

Stem Cell Technology in Medical Biotechnology

Assessment of the medical biotechnology industry in Singapore.

Seeing the industry’s promising future, Singapore has aimed to developed biotechnology as the fourth pillar of the economy (Ministry of Trade, 2000). Thus, this research work assesses the strength, weaknesses and competitive advantage of th...

Computational Tools; Indispensable Armamentarium of Medical Biotechnology

Objective: Computational infrastructure of medical biotechnology provides insight into elements of genomics, proteomics for understanding diseases and biological systems in a more comprehensive and systematic way. The present study exclusiv...

Students' knowledge of, and attitudes towards biotechnology revisited, 1995–2014: Changes in agriculture biotechnology but not in medical biotechnology

Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school...

Dynamics in business models: An empirical analysis of medical biotechnology firms in the Netherlands

Medical Biotechnology, Biopharmaceutics, Forensic Science and Bioinformatics