Academic Articles & Research Papers

ROS/Enzyme Dual-Responsive Drug Delivery System for Targeted Colorectal Cancer Therapy: Synergistic Chemotherapy, Anti-Inflammatory, and Gut Microbiota Modulation

Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, driven by chronic inflammation, gut microbiota dysbiosis, and complex tumor microenvironment interactions. Current therapies are limited by systemic toxicit...

Online Course Tailoring Design through Project-Based Learning Syntax in Fashion Studies

In learning Tailoring courses, understanding theory is a very important basis before students practice. Without a strong understanding of theory, tailoring practice will only be trial and error. Therefore, lecturers must ensure that each st...

Colonic stenting as bridge to surgery versus emergency surgery for management of acute left-sided malignant colonic obstruction: a multicenter randomized trial (Stent-in 2 study)

Abstract Background Acute left-sided colonic obstruction is most often caused by malignancy and the surgical treatment is associated with a high mortality and morbidity rate. Moreover, these operated patients end up with a temporary or perm...

Targeting the immune microenvironment in blastic plasmacytoid dendritic cell neoplasm: a genomic perspective.

Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review

Abstract Patchouli (“Guanghuoxiang”) or scientifically known as Pogostemon cablin Benth, belonging to the family Lamiaceae, has been used in traditional Chinse medicine (TCM) since the time of the Eastern Han dynasty. In TCM theory, patchou...

ROS-responsive tegafur-pheophorbide a conjugate-loaded microneedles for deep drug delivery and chemo-photodynamic therapy of superficial tumors.

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti-Tumor Immunity.

Hupehenine suppresses tumor cell phenotypes and modulates macrophage marker profiles in a diabeticmimetic colorectal cancer model.

Nursing interventions for managing treatment-related adverse effects of targeted anti-tumor therapies in adult cancer patients: a scoping review.

Machine learning models integrating 2D and 3D intratumoral heterogeneity features from multi-sequence MRI: accurate prediction of perineural invasion in pancreatic ductal adenocarcinoma.

Magnetic nanoplatforms at the tumor redox interface: from catalytic ROS amplification to ferroptosis and multimodal cancer therapy.

Pharmacological reprogramming of myeloid suppression in solid tumors: mechanisms, evidence standards for immune conversion, and biomarker-informed combinations.

Orally delivered exosome-like nanoparticles from Tetrastigma hemsleyanum Diels et Gilg remodel the gut-tumor immune axis to activate antitumor immunity.

SARS-CoV-2 inhibits EBV-dependent tumor proliferation through PLpro-mediated degradation of EBNA1.

Targeting the USP13-ACLY axis in tumor endothelial cells: Ginsenoside Rd suppresses pathological angiogenesis through metabolic-epigenetic reprogramming.

Phosphorylation of c-Myc at Ser62 via the protein kinase activity of acetaldehyde dehydrogenase 18A1 promotes tumor growth.

Tumor-targeted pan-RAS inhibition as a novel biologic therapy for diffuse midline glioma.

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells.

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD(+) biosynthesis.

Protocol for generating human organoid tumor transplantation and immune-human organoid tumor transplantation models for glioblastoma research.