Academic Articles & Research Papers

ROS/Enzyme Dual-Responsive Drug Delivery System for Targeted Colorectal Cancer Therapy: Synergistic Chemotherapy, Anti-Inflammatory, and Gut Microbiota Modulation

Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality, driven by chronic inflammation, gut microbiota dysbiosis, and complex tumor microenvironment interactions. Current therapies are limited by systemic toxicit...

Hybrid Coatings Based on Polyvinylpyrrolidone/Polyethylene Glycol Enriched with Collagen and Hydroxyapatite: Incubation Studies and Evaluation of Mechanical and Physiochemical Properties

Coating materials offers an intriguing solution for imparting inert implants with additional bioactive characteristics without changing underlying parameters such as mechanical strength. Metallic implants like endoprostheses or polymeric im...

Polyphenols and Pharmacological Screening of a Monarda fistulosa L. dry Extract Based on a Hydrodistilled Residue By-Product

This study aimed to determine the composition and content of polyphenols in the dry extract obtained from the hydrodistilled residue by-product of the wild bergamot (Monarda fistulosa L., Lamiaceae Martinov family) herb (MFDE) and to evalua...

Sub-chronic toxicity of polystyrene microplastics in Danio rerio: evidence from hematological, biochemical, oxidative stress, and histopathological biomarkers.

The relationship of homocysteine and its redox forms with renal toxicity after high-dose methotrexate treatment in patients with leukemia or lymphoma.

Screening of a chemogenetic library unveils dual-stage antiplasmodials with low cytotoxicity.

Surgical stress triggers widespread impairment of NK cell cytotoxicity and cytokine release.

Nanocurcumin Attenuates Doxorubicin-Induced Cardiotoxicity by Activating the Wnt/β-Catenin/GSK-3β Signaling Axis in Wistar Rats.

Mucin-rich environment shapes Pseudomonas aeruginosa cytotoxicity and phage-mediated epithelial protection.

Systemic Toxicity With Use of Apraclonidine Ophthalmic Drops in Pediatric Patients.

Adenoviral vector co-expressing ALDH1 and ADH1 mitigates alcohol toxicity and modulates glucose and lipid metabolism.

Effects of α‑Linolenic Acid and Arachidonic Acid on the Cytotoxicity and Steatosis of HepG2 Cells.

Equity in Neurotoxicity Care in the Era of Cancer Immunotherapy.

Experiences and coping strategies of time toxicity in young and middle-aged patients with lymphoma: a descriptive qualitative study.

Survival benefit and toxicity trade-offs of first-line chemoimmunotherapy in advanced gastric and gastroesophageal junction cancer: a meta-analysis of randomized trials.

The high price of innovation: addressing financial toxicity and healthcare inequity in gynecological malignancies.

From dietary exposure to systemic toxicity: organ-on-chip and multi-organ microphysiological systems for green food toxicology.

Caenorhabditis elegans in nanosafety research: dual effect of Escherichia coli ecocorona formation on single and combined toxicity of graphene oxide.

Carbon dots in cancer therapy: a novel approach to targeted drug delivery and reduced toxicity in gallbladder cancer.

Immune and inflammatory radiogenomics of radiotherapy-induced normal-tissue toxicity: genetic susceptibility, mechanisms, risk prediction, and clinical translation.