Academic Articles & Research Papers

Symptoms of Allergic Rhinitis in Women during Early Pregnancy Are Associated with Higher Prevalence of Allergic Rhinitis in Their Offspring

Background: Epigenetic control of gene expression profiles is a ubiquitous mechanism during cell differentiation, organogenesis and chronic inflammatory reactions. Recent studies have shown that allergen exposure during very early pregnancy...

The SKP1-like gene family of Arabidopsis exhibits a high degree of differential gene expression and gene product interaction during development.

The Arabidopsis thaliana genome encodes several families of polypeptides that are known or predicted to participate in the formation of the SCF-class of E3-ubiquitin ligase complexes. One such gene family encodes the Skp1-like class of poly...

Systematic engineering of synthetic minimal promoters for tunable transgene expression in mammalian cells.

Regulation of gastrin-releasing peptide gene expression in chickens.

Evaluation of soybean meal bioactive peptides and Spirulina powder as antibiotic alternatives on growth performance, physiological responses, and intestinal gene expression in broilers.

spOT-NMF: gene expression deconvolution via optimal transport with proximity-aware niche mapping for spatial transcriptomics.

Potential Health Benefits of Piceatannol-Rich Extracts from Passiflora edulis f. flavicarpa Seeds on Modulating Gene Expressions Related to Fat Metabolism and Muscle Development in C2C12 Myotubes.

Sulfur source-driven global remodeling of gene expression in the fuel-biodesulfurizing Rhodococcus qingshengii IGTS8.

Early vs late fusion of qMIDS with machine learning based classifiers for oral cancer diagnosis from gene expression data.

LncRNA-Top: Controlled deep learning approaches for lncRNA gene regulatory relationship annotations across different platforms

Summary: By soaking microRNAs (miRNAs), long non-coding RNAs (lncRNAs) have the potential to regulate gene expression. Few methods have been created based on this mechanism to anticipate the lncRNA-gene relationship prediction. Hence, we pr...

Functional annotation of the human retinal pigment epithelium transcriptome

Abstract Background To determine level, variability and functional annotation of gene expression of the human retinal pigment epithelium (RPE), the key tissue involved in retinal diseases like age-related macular degeneration and retinitis ...

Abnormal X : autosome ratio, but normal X chromosome inactivation in human triploid cultures

Abstract Background X chromosome inactivation (XCI) is that aspect of mammalian dosage compensation that brings about equivalence of X-linked gene expression between females and males by inactivating one of the two X chromosomes (Xi) in nor...

Genetics : a conceptual approach

Introduction to Genetics Genetics Is Important to Us Individually, to Society, and to the Study of Biology Humans Have Been Using Genetics for Thousands of Years A Few Fundamental Concepts Are Important for the Start of Our Journey into Gen...

The Genetics of Eating Disorders

Over the past decade, considerable advances have been made in understanding genetic influences on eating pathology. Eating disorders aggregate in families, and twin studies reveal that additive genetic factors account for approximately 40% ...

Concepts of Genetics

Part 1 Heredity and the phenotype: cell division - mitosis and meosis Mendalian genetics modification of Mendelian ratios linkage and chromosome mapping in eukaryotes recombination and mapping in bacteria and bacteriophages extensions of ge...

Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice

Objective: Carbohydrate response element binding protein (ChREBP) is a transcription factor that responds to glucose and activates genes involved in the glycolytic and lipogenic pathways. Recent studies have linked adipose ChREBP to insulin...

CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression

Abstract Background The stiffness of the matrix is closely related to the progression of hepatocellular carcinoma (HCC). Although direct targeting of stromal rigidity in HCC remains a clinical challenge, cancer-associated fibroblasts (CAFs)...

A110

Tumor necrosis factor alpha (TNF) is a multifunctional cytokine, which possesses various biologic functions depending on the type of the cells and the physiological context. TNF is synthesized by immune cells as well as malignant cells. Acc...

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice

Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compar...

Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases

Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...