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Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology

Alexey A. Shadrin, Tobias Kaufmann, Dennis van der Meer, Clare E. Palmer et al. • NeuroImage (2021)

Brain morphology has been shown to be highly heritable, yet only a small portion of the heritability is explained by the genetic variants discovered so far. Here we extended the Multivariate Omnibus Statistical Test (MOSTest) and applied it...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.neuroimage.2021.118603

CD56-Negative Extranodal Natural Killer/T-Cell Lymphoma: A Retrospective Study in 443 Patients Treated by Chemotherapy With or Without Asparaginase

Jing Yang, Pengfei Li, Pengfei Li, Pengfei Li et al. • Frontiers in Immunology (2022)

ObjectiveExtranodal natural killer/T cell lymphoma (NKTCL) is an aggressive EBV-related lymphoma, originating from NK cells or T cells. Previous study demonstrated that CD56 negative NKTCL should be recognized as a distinct subtype. In this...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2022.829366

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists

Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology (2024)

The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol31090369

Genetic impact of non-consanguineous marriages in Saudi Arabia.

Mohammed Alyahya, Taghrid Aloraini, Youseef Al-Harbi, Lamia Alsubaie et al. • Journal of Biochemical and Clinical Genetics (2022)

Background: Physicians and geneticists face challenges in making accurate diagnoses during clinical evaluations; affecting patients and clinicians. The aim of this study was to estimate the hit rate of the non-consanguineous population. Mor...

DOAJ Open Access (DOAJ) DOI: 10.24911/JBCGenetics/183-1664872492

From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder

Chunyu Pan, Ying Ma, Lifei Wang, Yan Zhang et al. • Brain Sciences (2024)

Major Depressive Disorder (MDD) is a significant neurological condition associated with aberrations in brain functional networks. Traditional studies have predominantly analyzed these from a network topology perspective. However, given the ...

DOAJ Open Access (DOAJ) DOI: 10.3390/brainsci14050509