R Research Papers

Twins‐like nanodrugs synchronously transport in blood and coalesce inside tumors for sensitive ultrasound imaging and triggerable penetrative drug delivery

Abstract Nanodrugs capable of aggregating in the tumor microenvironment (TME) have demonstrated great efficiency in improving the therapeutic outcome. Among various approaches, the strategy utilizing electrostatic interaction as a driving f...

External Thermal Insulation Composite Systems: Critical Parameters for Surface Hygrothermal Behaviour

External Thermal Insulation Composite Systems (ETICS) are often used in Europe. Despite its thermal advantages, low cost, and ease of application, this system has serious problems of biological growth causing the cladding defacement. Recent...

Simulation and experimental verification of the edge effect of composites on the infiltration process of RTM forming

To study the influence of edge effects on the resin filling flow pattern in the RTM process of composite materials, the finite element software PAM-RTM was used to simulate and analyze the impregnation process of the blade preforms in RTM.B...

Effect of Ageing on a Novel Cobalt-Free Precipitation-Hardenable Martensitic Alloy Produced by SLM: Mechanical, Tribological and Corrosion Behaviour

This study investigates the mechanical, tribological, and electrochemical behaviour of a novel precipitation-hardenable martensitic alloy produced by selective laser melting (SLM). The alloy was specifically engineered with an optimised com...

Second hyperpolarizability of hexagonal graphene quantum dots: Effects of size and structural defects

Graphene quantum dots (GQDs) are nanosized fragments of graphene containing a bandgap caused by edge effects and quantum confinement. These features enable GQDs to have attractive photonics applications. During the preparation of graphene n...

Idiopathic pulmonary fibrosis: Addressing the current and future therapeutic advances along with the role of Sotatercept in the management of pulmonary hypertension

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive and debilitating lung disease characterized by irreversible scarring of the lungs. The cause of IPF is unknown, but it is thought to involve a combination of genetic a...

Inclusions in melting process of titanium and titanium alloys

This paper summarizes melting methods of titanium and titanium alloy, such as vacuum arc melting (VAR) and electron beam cold hearth melting (EBCHM), and the related inclusions formed when using these melting methods. Low-density inclusions...

High-temperature Infrared Transmission of Free-standing Diamond Films

The combination of low absorption and extreme mechanical and thermal properties make diamond a compelling choice for some more extreme far infrared (8-12 μm) window applications. The optical properties of CVD diamond at elevated temperature...

Biocompatible Nanocarriers for Enhanced Cancer Photodynamic Therapy Applications

In recent years, the role of nanotechnology in drug delivery has become increasingly important, and this field of research holds many potential benefits for cancer treatment, particularly, in achieving cancer cell targeting and reducing the...

Highly Sensitive and Specific Detection of Influenza A Viruses Using Bimolecular Fluorescence Complementation (BiFC) Reporter System

In this study, we developed a highly sensitive and specific bimolecular fluorescence complementation (BiFC)-based influenza A virus (IAV)-sensing system by combining a galactose/glucose-binding protein (GGBP) with an N-terminal large domain...

Extraction of nano-crystalline cellulose for development of aerogel: Structural, morphological and antibacterial analysis

In the present decades, nanocellulose has been very popular in the field of nanotechnology and is receiving much attention from researchers because of its advantageous physicochemical properties, high aspect ratio, and high specific strengt...

The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State-of-the-Art Review

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can lead to end-stage liver disease needing a liver transplant. Many pharmacological approaches are used to reduce the disease progression in NAFLD. However, cu...

Advances of medical nanorobots for future cancer treatments

Abstract Early detection and diagnosis of many cancers is very challenging. Late stage detection of a cancer always leads to high mortality rates. It is imperative to develop novel and more sensitive and effective diagnosis and therapeutic ...

A nanotechnology-based approach to enhance caraway (Carum carvi L.) productivity, chemical, biochemical and essential oil under salinity stress

Salt stress is an abiotic stressor that adversely affects the growth and productivity of caraway, an important aromatic plant. A randomized complete split-plot design was used to determine the nanoparticles of zinc oxide (ZnO NPs) effects a...

Decellularized Placental Sponge: A Platform for Coculture of Mesenchymal Stem Cells/Macrophages to Assess an M2 Phenotype and Osteogenic Differentiation In Vitro and In Vivo

Silver Nanoparticles Suppress Apple Fire Blight: Antibacterial Activity, Reduced Carbohydrate-Containing EPS Content, and Altered Host Antioxidant Responses

The present study evaluated the phytoprotective activity of silver nanoparticles stabilized with sodium amphopolycarboxyglycinate (AgNPs-APCG) against apple fire blight caused by Erwinia amylovora. A highly colloidally stable AgNPs-APCG dis...

Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives

The antitumor drug 3-amino-1,2,4-benzotriazine-1,4-dioxide (tirapazamine, TPZ (1)) along with a number of newly synthesized tirapazamine derivatives (TPZs) bearing substitutions at the 3-amine position of TPZ (1) were estimated for their an...

In silico design of a triple-negative breast cancer vaccine by targeting cancer testis antigens

Introduction: Triple-negative breast cancer (TNBC) is an important subtype of breast cancer, which occurs in the absence of estrogen, progesterone and HER-2 receptors. According to the recent studies, TNBC may be a cancer testis antigen (CT...

Development of a New 24-bit High-Performance Chipless RFID Tag for Accurate Identification in IoT Systems

Chipless RFID has the potential to bring in a paradigm change in industrial applications, notably in the world of the Internet of Things (IoT). This wireless technology permits distant identification, sensing, and tracking, giving tremendou...

Heat transfer augmentation of Al2O3-Cu/water hybrid nanofluid in circular duct with inserts

Nanotechnology has opened up new avenues for industrial efficiency and performance. The Al2O3-Cu/water hybrid nanofluid with and without insert is analyzed numerically and validated to show heat transfer enhancement. A circular duct with in...