Showing 20 of 13,979 academic articles
Pei-Iun Hsieh, Te-Hsuan Huang, Jeng-Min Chiou, Jen-Hau Chen et al. • Epidemiology and Health
(2024)
The Taiwan Initiative for Geriatric Epidemiological Research (TIGER) was founded in 2011 to elucidate the interrelationships among various predictors of global and domain-specific cognitive impairment, with the aim of identifying older adul...
DOAJ
Open Access (DOAJ)
DOI: 10.4178/epih.e2024057
Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali et al. • Cell Reports
(2018)
Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compar...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.celrep.2018.10.070
Xiao Lin, Jun-Jie Yang, Bei Huang, Peng-Xin Wang et al. • Experimental Gerontology
(2026)
Background: BMI cannot distinguish fat distribution and may mask the true effects of different fat depots on bone mineral density (BMD). To investigate sex- and age-specific associations between fat distribution and BMD and its mediating ro...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113301
Chen Chen, Qi Zhou, Ruiyue Yang, Zhu Wu et al. • Ecotoxicology and Environmental Safety
(2021)
Background: Excessive copper (Cu) has risky effect on insulin resistance (IR), oxidative stress and inflammation. Instead, some studies reported serum Cu to be protective for non-alcoholic fatty liver disease (NAFLD). The aim of this study ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ecoenv.2021.112295
Hsiao-Mei Chen, Ching-Min Chen • International Journal of Gerontology
(2017)
Background: There have been many studies reviewing quality of life (QoL) of older population and found an inverse association between QoL and chronic diseases. However, previous studies have focused only on that of people with specific dise...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ijge.2016.07.002
Claudia Contreras, Diana Paola Córdoba‐Rodríguez, Robinson Cuadros, José Ricardo Jauregui et al. • JCSM Communications
(2026)
ABSTRACT Background Secondary sarcopenia driven by chronic disease, acute illness, immobilization, malnutrition or treatment‐related factors contributes to functional decline, falls, disability, readmission and mortality. In Colombia, uneve...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/rco2.70051
Maria Luiza Lima-Silva, Karen Cecília Lima Torres, Juliana Vaz de Melo Mambrini, Nathalia Coimbra Brot et al. • Experimental Gerontology
(2024)
Immunosenescence is a phenomenon caused by changes in the immune system, and part of these changes involves an increase in circulating immunological biomarkers, a process known as “Inflammaging.” Inflammaging can be associated with many dis...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112433
Min-Jeong Kim, Eun-Sang Hwang, Kwan Joong Kim, Sungho Maeng et al. • Antioxidants
(2021)
Epigallocatechin gallate (EGCG) is a major flavan-3-ol of green tea polyphenols that exhibits various beneficial health effects, including antioxidant, anti-bacterial, and anti-inflammatory properties. This study aimed to evaluate whether E...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/antiox11010001
Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology
(2026)
Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113057
Yan Zhang, Ling Jiang, Jinyu Zhu, Sijia Shen et al. • BMJ Paediatrics Open
(2026)
Background Proper discharge preparation by family caregivers is essential for improving the growth and development of preterm infants and lowering their readmission rates. Within China’s unique family cultural context, intergenerational car...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjpo-2026-004695
PMC: PMC13691880
Sillas Oliveira Leonel Júnior, Mateus Dias Antunes, Ramon Gustavo de Moraes Ovando, Ana Paula Serra de Araújo et al. • Geriatrics, Gerontology and Aging
(2024)
OBJECTIVE: To analyze the behavior of blood pressure and heart rate in elderly people practicing physical exercises in Maringá, Paraná, Brazil. METHODS: 70 elderly volunteers were evaluated, 41 women and 29 men, with a mean age of 67.2 ± 6....
DOAJ
Open Access (DOAJ)
DOI: 10.5327/Z2447-211520171700042
Meng Zhang, Ping He, Zhigang Bian • Frontiers in Molecular Neuroscience
(2021)
Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnmol.2021.685143
Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology
(2026)
Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s42003-026-09966-4
Lan Chen, Jing-Xin Zhang, Dong-Ge Liu, Hong-Gang Liu • Diagnostics
(2023)
This paper illustrates a rare syndrome of multiple endocrine neoplasia type 2A (MEN2A) in a family of three generations. In our case, the father, son and one daughter developed phaeochromocytoma (PHEO) and medullary thyroid carcinoma (MTC) ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/diagnostics13050955
Hanghang Gan, Yu Yan, Shanshan Jia, Yingqiang Guo et al. • Experimental Gerontology
(2025)
Object: To explore the effects of different combinations of calorie intake and exercise on all-cause, cardiovascular and cancer mortality. Methods: Data from the National Health and Nutrition Examination Survey (NHANES) were analyzed. Weigh...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2025.112805
Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu et al. • Experimental Gerontology
(2024)
The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cel...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112633
Victoria McArthur, Susan Everington, Martyn Patel • Archives of Gerontology and Geriatrics Plus
(2024)
Introduction: Dementia is a global health priority, with an increasing percentage of overall hospital bed days occupied by people with dementia (PWD). This combined with increased demand and availability of complex scanning means that there...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.aggp.2024.100087
Luciano Magalhães Vitorino BSN, MSc, Gail Low RN, BSN, MA, PhD, Lucila Amaral Carneiro Vianna PhD • Gerontology and Geriatric Medicine
(2016)
Objective: This study examined the effect of Positive and Negative Spiritual and Religious Coping (SRC) upon older Brazilian’s quality of life (QOL). Method: A secondary analysis of data collected from 77 nursing home residents (NHRs; M age...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/2333721416658140
Yi-Shan Jiang, Hong Shi, Yu-Ting Kang, Ji Shen et al. • BMC Geriatrics
(2023)
Abstract Background The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how ...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-023-04089-5
Yan Zhao, Tingting Chen, Conghua Ji, Yuxin Shang et al. • Experimental Gerontology
(2026)
Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it is unclear whether ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2025.113010