R Research Papers

Preclinical Characterization of Mobocertinib Highlights the Putative Therapeutic Window of This Novel EGFR Inhibitor to EGFR Exon 20 Insertion Mutations

Introduction: EGFR exon 20 insertion mutations account for 10% of all EGFR mutations and are mostly insensitive to approved EGFR tyrosine kinase inhibitors (EGFR TKIs). Novel EGFR TKIs have been developed or repurposed for these mutants. A ...

Investigating Professional Development Policy and Practice for Educational Policy-Makers in Vietnam: An Exploratory Study

There has been a large number of studies concerning professional development at the micro level. However, little research has been particularly conducted to investigate professional development at the macro level. This study aims to explore...

Study on evaluation of normal range of maximum mouth opening among Indian adults using three finger index: A descriptive study

Introduction: Early recognition of decreased or limited mouth opening in many pathological conditions is necessary for prompt diagnosis and to plan the treatment options judiciously. Therefore, it is essential to establish what constitutes ...

A cross-sectional assessment of knowledge, attitude, and practice of dentists regarding acute herpetic gingivostomatitis in children

Acute herpetic gingivostomatitis (AHGS) is the oral manifestation of HVS-1 primary infection. Despite being a self-limiting infection, AHGS can progress to severe complications. Dentists should be prepared to correctly diagnose and treat th...

The role of feedback in supporting trainees who underperform in clinical environments

IntroductionUnderperformance in clinical environments can be costly and emotional for all stakeholders. Feedback is an important pedagogical strategy for working with underperformance – both formal and informal strategies can make a differe...

Tungsten Oxide-contained PEO Coatings on Ti–6Al‑4 V Alloys: Enhanced Surface Characteristics and Bioactivity for Bio-implant

Perceptions of medical students on oral healthcare in Iran: a cross-sectional study

Anticancer, antioxidant and antibacterial potential of L-Glutaminase (Streptomyces roseolus strain ZKB1) capped silver and zinc oxide nanoparticles and its molecular characterization

Abstract The current investigation reports anti-cancer, antioxidant and antibacterial potential of L-Glutaminase (Streptomyces roseolus strain ZKB1) and L-Glutaminase capped nanoparticles. The highest L-Glutaminase production of 9.57 U/mL w...

Perception of dental trauma by community health workers in the Amazon region

The high prevalence of dental trauma among the population highlights the importance of the preventative actions taken after trauma to preserve the integrity of the dental organ. The present study aimed to evaluate the perception of the Comm...

Intramucosal nevus on the posterior hard palate

Evaluation of dentinal tubule penetration of a novel nano calcium hydroxide–zinc oxide intracanal medicament: An in vitro pilot study

Background: Residual microorganisms within dentinal tubules remain a key factor in persistent endodontic infections. Therefore, the ability of intracanal medicaments to effectively penetrate these tubules is critical for post-endodontic tre...

Minimally invasive approach in esthetic dentistry: composite resin versus ceramics veneers

Unsatisfactory anatomical shape of anterior tooth promotes disharmony in the smile esthetics. The conservative dental esthetic reestablishment treatments has been improved and evaluated with the development of adhesive materials. The adhesi...

Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil

ABSTRACT Pigmented oral lichen planus (OLP) is a chronic, immune‐mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typi...

Triple-Layered Closure Of An Oroantral Fistula: A Case Report

Introduction: An oroantral fistula (OAF) is an abnormal connection between the oral cavity and the maxillary sinus, usually occurred after the removal of maxillary premolar and molar teeth. Many techniques have been described for closure of...

The Psychological Impact of the COVID-19 Pandemic on Frontline Healthcare Workers. A Systematic Review and a Meta-Analysis

Introduction: The COVID-19 pandemic has created a chronically stressful work environment for healthcare workers, increasing the negative psychological effects experienced. Aims: The authors of this systematic review and meta-analysis aime...

Viral evolution: Influenza evolves - From rhetoric to reality?

Evaluating Adenomyosis with Transvaginal Sonography: Diagnostic Precision and Clinical Relevance

Background: Adenomyosis is an important benign gynecological condition among females with variable signs and symptoms. Prompt detection of suspicious cases is important for the effective management of the disease. The objective of the curre...

The Effectiveness of Using Pulpotec® in Treatment of Pulpitis by Pulpotomy of Vital Deciduous Molar and Vital Immature Permanent Molar

Aims: To evaluate the effect of two types of disinfectant solutions(2% alkaline glutaraldehyde, 1% sodium hypochlorite) in wettability of three types of elastomeric impression materials (light body) which are used in crown and bridge restor...

Analysis of the cephalometric pattern of Brazilian achondroplastic adult subjects

OBJECTIVE: The aim of this study was to assess the position of the cranial base, maxilla, and mandible of Brazilian achondroplastic adult subjects through cephalometric measurements of the cranio-dento-facial complex, and to compare the res...

Resposta pulpar frente a agressões: Lesões inflamatórias

Os mecanismos de aparecimento das inflamações é o mesmo. O flogógeno ou agente inflamatório age sobre os tecidos e induz a liberação de mediadores químicos que ao agirem nos receptores existentes nas células da micro-circulação e nos leucóc...