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Unanticipated intermediates during isopenicillin N synthase catalysis identified by time-resolved X-ray free-electron laser studies.
Rabe P, Makita H, Southwart R, Thomas MG, Kazaks M, Basak S, Zhou T, Myers WK, Doyle MD, Simon PS, Hayama S, Mosselmans JFW, Stead AT, Oluwole AO, Sami M, Clifton I, Aller P, Bhowmick A, Tumber A, Kamps JJAG, Calvopiña K, Butryn A, Bosman R, Cheema A, Welsh J, Linyard JDS, Foster FJH, Lang PA, de Munnik M, Keable SM, Dasgupta M, Kim IS, Bogacz I, Chatterjee K, Sutherlin KD, Kaminsky CJ, Brem J, McDonough MA, Redfield C, Montgomery JRD, Mycroft C, Shilova A, Devenish N, Poitevin FP, Dehe S, Tiwari V, Sanchez H, Rosenberg DJ, Hunter MS, Gee LB, Bergmann U, Alonso-Mori R, Park J, Owada S, Tono K, Axford D, Owen RL, Paley DW, Sauter NK, Mittan-Moreau D, Brewster AS, Robinson CV, Yachandra VK, Yano J, Suna E, Christov CZ, Orville AM, Kern JF, Schofield CJ
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